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New imidazolidinedione derivatives as antimalarial agents.
Zhang L, Sathunuru R, Luong T, Melendez V, Kozar MP, Lin AJ. Zhang L, et al. Among authors: kozar mp. Bioorg Med Chem. 2011 Feb 15;19(4):1541-9. doi: 10.1016/j.bmc.2010.12.028. Epub 2010 Dec 16. Bioorg Med Chem. 2011. PMID: 21282058
Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy.
Milner E, Sousa J, Pybus B, Auschwitz J, Caridha D, Gardner S, Grauer K, Harris E, Hickman M, Kozar MP, Lee P, Leed S, Li Q, Melendez V, Moon J, Ngundam F, O'Neil M, Parriott S, Potter B, Sciotti R, Tangteung A, Dow GS. Milner E, et al. Among authors: kozar mp. Eur J Drug Metab Pharmacokinet. 2012 Mar;37(1):17-22. doi: 10.1007/s13318-012-0080-2. Eur J Drug Metab Pharmacokinet. 2012. PMID: 22314893
Malaria causal prophylactic activity of imidazolidinedione derivatives.
Guan J, Wang X, Smith K, Ager A, Gettayacamin M, Kyle DE, Milhous WK, Kozar MP, Magill AJ, Lin AJ. Guan J, et al. Among authors: kozar mp. J Med Chem. 2007 Nov 29;50(24):6226-31. doi: 10.1021/jm7009815. Epub 2007 Oct 30. J Med Chem. 2007. PMID: 17967003
21 results