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Page 1
Characterization of Enzymes Involved in Nintedanib Metabolism in Humans.
Nakashima S, Sato R, Fukami T, Kudo T, Hashiba S, Morinaga G, Nakano M, Ludwig-Schwellinger E, Matsui A, Ishiguro N, Ebner T, Nakajima M. Nakashima S, et al. Among authors: ludwig schwellinger e. Drug Metab Dispos. 2023 Jun;51(6):733-742. doi: 10.1124/dmd.122.001113. Epub 2023 Mar 16. Drug Metab Dispos. 2023. PMID: 36927840
Hepatic differentiation of human iPSCs in different 3D models: A comparative study.
Meier F, Freyer N, Brzeszczynska J, Knöspel F, Armstrong L, Lako M, Greuel S, Damm G, Ludwig-Schwellinger E, Deschl U, Ross JA, Beilmann M, Zeilinger K. Meier F, et al. Among authors: ludwig schwellinger e. Int J Mol Med. 2017 Dec;40(6):1759-1771. doi: 10.3892/ijmm.2017.3190. Epub 2017 Oct 16. Int J Mol Med. 2017. PMID: 29039463 Free PMC article.
Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species.
Taub ME, Ludwig-Schwellinger E, Ishiguro N, Kishimoto W, Yu H, Wagner K, Tweedie D. Taub ME, et al. Among authors: ludwig schwellinger e. Chem Res Toxicol. 2015 Jan 20;28(1):103-15. doi: 10.1021/tx500380t. Epub 2015 Jan 5. Chem Res Toxicol. 2015. PMID: 25489797
Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities.
Ohtsuki S, Schaefer O, Kawakami H, Inoue T, Liehner S, Saito A, Ishiguro N, Kishimoto W, Ludwig-Schwellinger E, Ebner T, Terasaki T. Ohtsuki S, et al. Among authors: ludwig schwellinger e. Drug Metab Dispos. 2012 Jan;40(1):83-92. doi: 10.1124/dmd.111.042259. Epub 2011 Oct 12. Drug Metab Dispos. 2012. PMID: 21994437