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Page 1
Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma.
Nilsson M, Rhedin M, Hendrickx R, Berglund S, Piras A, Blomgran P, Cavallin A, Collins M, Dahl G, Dekkak B, Ericsson T, Hagberg N, Holmberg AA, Leffler A, Lundqvist AJ, Markou T, Pinkerton J, Rönnblom L, Siu S, Taylor V, Wennberg T, Zervas D, Laurence ADJ, Mitra S, Belvisi MG, Birrell M, Borde A. Nilsson M, et al. Among authors: lundqvist aj. Drug Des Devel Ther. 2022 Aug 31;16:2901-2917. doi: 10.2147/DDDT.S354291. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36068788 Free PMC article.
Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation.
Sadiq MW, Holz O, Ellinghusen BD, Faulenbach C, Müller M, Badorrek P, Eriksson UG, Fridén M, Stomilovic S, Lundqvist AJ, Hohlfeld JM. Sadiq MW, et al. Among authors: lundqvist aj. Br J Pharmacol. 2021 Nov;178(22):4440-4451. doi: 10.1111/bph.15621. Epub 2021 Aug 11. Br J Pharmacol. 2021. PMID: 34250588 Free article.
Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata.
Mattsson J, Israelsson E, Björhall K, Yrlid LF, Thörn K, Thorén A, Toledo EA, Jinton L, Öberg L, Wingren C, Tapani S, Jackson SG, Skogberg G, Lundqvist AJ, Hendrickx R, Cavallin A, Österlund T, Grimster NP, Nilsson M, Åstrand A. Mattsson J, et al. Among authors: lundqvist aj. Skin Health Dis. 2023 Jan 29;3(3):e209. doi: 10.1002/ski2.209. eCollection 2023 Jun. Skin Health Dis. 2023. PMID: 37275428 Free PMC article.
Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma.
Munck Af Rosenschöld M, Johannesson P, Nikitidis A, Tyrchan C, Chang HF, Rönn R, Chapman D, Ullah V, Nikitidis G, Glader P, Käck H, Bonn B, Wågberg F, Björkstrand E, Andersson U, Swedin L, Rohman M, Andreasson T, Bergström EL, Jiang F, Zhou XH, Lundqvist AJ, Malmberg A, Ek M, Gordon E, Pettersen A, Ripa L, Davis AM. Munck Af Rosenschöld M, et al. Among authors: lundqvist aj. J Med Chem. 2019 Sep 12;62(17):7769-7787. doi: 10.1021/acs.jmedchem.9b00555. Epub 2019 Aug 30. J Med Chem. 2019. PMID: 31415176