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Page 1
Non-specific binding of compounds in in vitro metabolism assays: a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models.
Xenobiotica. 2022 Aug;52(8):943-956. doi: 10.1080/00498254.2022.2132426.
Xenobiotica. 2022.
PMID: 36222269
Animal versus human oral drug bioavailability: do they correlate?
Musther H, Olivares-Morales A, Hatley OJ, Liu B, Rostami Hodjegan A.
Musther H, et al.
Eur J Pharm Sci. 2014 Jun 16;57(100):280-91. doi: 10.1016/j.ejps.2013.08.018. Epub 2013 Aug 26.
Eur J Pharm Sci. 2014.
PMID: 23988844
Free PMC article.
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Predictive Performance of Physiologically Based Pharmacokinetic Modelling of Beta-Lactam Antibiotic Concentrations in Adipose, Bone, and Muscle Tissues.
De Sutter PJ, De Cock P, Johnson TN, Musther H, Gasthuys E, Vermeulen A.
De Sutter PJ, et al. Among authors: musther h.
Drug Metab Dispos. 2023 Apr;51(4):499-508. doi: 10.1124/dmd.122.001129. Epub 2023 Jan 13.
Drug Metab Dispos. 2023.
PMID: 36639242
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The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model.
Musther H, Harwood MD, Yang J, Turner DB, Rostami-Hodjegan A, Jamei M.
Musther H, et al.
J Pharm Sci. 2017 Sep;106(9):2826-2838. doi: 10.1016/j.xphs.2017.05.003. Epub 2017 May 8.
J Pharm Sci. 2017.
PMID: 28495566
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Are Physiologically Based Pharmacokinetic Models Reporting the Right C(max)? Central Venous Versus Peripheral Sampling Site.
Musther H, Gill KL, Chetty M, Rostami-Hodjegan A, Rowland M, Jamei M.
Musther H, et al.
AAPS J. 2015 Sep;17(5):1268-79. doi: 10.1208/s12248-015-9796-7. Epub 2015 Jun 23.
AAPS J. 2015.
PMID: 26100012
Free PMC article.
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