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Page 1
1,3-Benzodioxole-Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin-Bound Structure.
ChemMedChem. 2021 Sep 16;16(18):2882-2894. doi: 10.1002/cmdc.202100363. Epub 2021 Jul 16.
ChemMedChem. 2021.
PMID: 34159741
Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives.
Muthiah D, Henshaw GK, DeBono AJ, Capuano B, Scammells PJ, Callaghan R.
Muthiah D, et al.
Drug Metab Dispos. 2019 Feb;47(2):164-172. doi: 10.1124/dmd.118.083188. Epub 2018 Nov 26.
Drug Metab Dispos. 2019.
PMID: 30478158
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Synthesis and Pharmacological Evaluation of Noscapine-Inspired 5-Substituted Tetrahydroisoquinolines as Cytotoxic Agents.
Devine SM, Yong C, Amenuvegbe D, Aurelio L, Muthiah D, Pouton C, Callaghan R, Capuano B, Scammells PJ.
Devine SM, et al. Among authors: muthiah d.
J Med Chem. 2018 Sep 27;61(18):8444-8456. doi: 10.1021/acs.jmedchem.8b00986. Epub 2018 Sep 14.
J Med Chem. 2018.
PMID: 30156410
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Primary and secondary perforator-based flap-in-flap reconstructions of postexcisional head and neck soft tissue defects.
Balakrishnan DTM, Muthiah DM, Ramachandran DV, Jaganmohan DJ.
Balakrishnan DTM, et al. Among authors: muthiah dm.
JPRAS Open. 2020 May 21;25:30-39. doi: 10.1016/j.jpra.2020.05.001. eCollection 2020 Sep.
JPRAS Open. 2020.
PMID: 32637529
Free PMC article.
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The synthesis and biological evaluation of multifunctionalised derivatives of noscapine as cytotoxic agents.
Debono AJ, Mistry SJ, Xie J, Muthiah D, Phillips J, Ventura S, Callaghan R, Pouton CW, Capuano B, Scammells PJ.
Debono AJ, et al. Among authors: muthiah d.
ChemMedChem. 2014 Feb;9(2):399-410. doi: 10.1002/cmdc.201300395. Epub 2013 Dec 11.
ChemMedChem. 2014.
PMID: 24339417
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Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells.
Muthiah D, Callaghan R.
Muthiah D, et al.
Eur J Pharmacol. 2017 Nov 15;815:127-137. doi: 10.1016/j.ejphar.2017.09.001. Epub 2017 Sep 11.
Eur J Pharmacol. 2017.
PMID: 28912036
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