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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1990 2
1992 1
1996 1
1997 3
1998 2
1999 2
2000 6
2001 4
2002 4
2003 9
2004 7
2005 14
2006 9
2007 14
2008 12
2009 15
2010 15
2011 11
2012 19
2013 16
2014 11
2015 5
2016 9
2017 5
2018 10
2019 6
2020 11
2021 9
2022 6
2023 5
2024 2

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213 results

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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Among authors: obach rs. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.
The Importance of Tracking "Missing" Metabolites: How and Why?
Wang S, Ballard TE, Christopher LJ, Foti RS, Gu C, Khojasteh SC, Liu J, Ma S, Ma B, Obach RS, Schadt S, Zhang Z, Zhang D. Wang S, et al. Among authors: obach rs. J Med Chem. 2023 Dec 14;66(23):15586-15612. doi: 10.1021/acs.jmedchem.3c01293. Epub 2023 Sep 28. J Med Chem. 2023. PMID: 37769129 Review.
Metabolic activation in drug-induced liver injury.
Leung L, Kalgutkar AS, Obach RS. Leung L, et al. Among authors: obach rs. Drug Metab Rev. 2012 Feb;44(1):18-33. doi: 10.3109/03602532.2011.605791. Epub 2011 Sep 23. Drug Metab Rev. 2012. PMID: 21939431 Review.
Managing the challenge of chemically reactive metabolites in drug development.
Park BK, Boobis A, Clarke S, Goldring CE, Jones D, Kenna JG, Lambert C, Laverty HG, Naisbitt DJ, Nelson S, Nicoll-Griffith DA, Obach RS, Routledge P, Smith DA, Tweedie DJ, Vermeulen N, Williams DP, Wilson ID, Baillie TA. Park BK, et al. Among authors: obach rs. Nat Rev Drug Discov. 2011 Apr;10(4):292-306. doi: 10.1038/nrd3408. Nat Rev Drug Discov. 2011. PMID: 21455238 Review.
213 results