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Page 1
Bioactivation of cyclopropyl rings by P450: an observation encountered during the optimisation of a series of hepatitis C virus NS5B inhibitors.
Xenobiotica. 2018 Dec;48(12):1215-1226. doi: 10.1080/00498254.2017.1409915. Epub 2017 Dec 12.
Xenobiotica. 2018.
PMID: 29182424
Phosphocholine conjugation: an unexpected in vivo conjugation pathway associated with hepatitis c ns5b inhibitors featuring a bicyclo[1.1.1]pentane.
Zhuo X, Cantone JL, Wang Y, Leet JE, Drexler DM, Yeung KS, Huang XS, Eastman KJ, Parcella KE, Mosure KW, Soars MG, Kadow JF, Johnson BM.
Zhuo X, et al. Among authors: parcella ke.
Drug Metab Dispos. 2016 Aug;44(8):1332-1340. doi: 10.1124/dmd.115.069062. Epub 2016 Mar 9.
Drug Metab Dispos. 2016.
PMID: 26961241
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