Patilea-Vrana G[au] - Search Results

Year	Number of Results
2016	1
2017	1
2018	2
2019	4
2021	1
2022	1
2023	1
2024	0

1

SGN-B6A: A New Vedotin Antibody-Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications.

Lyon RP, Jonas M, Frantz C, Trueblood ES, Yumul R, Westendorf L, Hale CJ, Stilwell JL, Yeddula N, Snead KM, Kumar V, Patilea-Vrana GI, Klussman K, Ryan MC. Lyon RP, et al. Among authors: patilea vrana gi. Mol Cancer Ther. 2023 Dec 1;22(12):1444-1453. doi: 10.1158/1535-7163.MCT-22-0817. Mol Cancer Ther. 2023. PMID: 37619980 Free PMC article.

2

A marijuana-drug interaction primer: Precipitants, pharmacology, and pharmacokinetics.

Cox EJ, Maharao N, Patilea-Vrana G, Unadkat JD, Rettie AE, McCune JS, Paine MF. Cox EJ, et al. Among authors: patilea vrana g. Pharmacol Ther. 2019 Sep;201:25-38. doi: 10.1016/j.pharmthera.2019.05.001. Epub 2019 May 7. Pharmacol Ther. 2019. PMID: 31071346 Free PMC article. Review.

3

Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities.

Zhang D, Hop CECA, Patilea-Vrana G, Gampa G, Seneviratne HK, Unadkat JD, Kenny JR, Nagapudi K, Di L, Zhou L, Zak M, Wright MR, Bumpus NN, Zang R, Liu X, Lai Y, Khojasteh SC. Zhang D, et al. Among authors: patilea vrana g. Drug Metab Dispos. 2019 Oct;47(10):1122-1135. doi: 10.1124/dmd.119.086744. Epub 2019 Jul 2. Drug Metab Dispos. 2019. PMID: 31266753 Free PMC article. Review.

4

Characterizing and Quantifying Extrahepatic Metabolism of (-)-Δ⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, (±)-11-Hydroxy-Δ⁹-THC (11-OH-THC).

Kumar AR, Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Kumar AR, et al. Among authors: patilea vrana gi. Drug Metab Dispos. 2022 Jun;50(6):734-740. doi: 10.1124/dmd.122.000868. Epub 2022 Apr 3. Drug Metab Dispos. 2022. PMID: 35370140 Free PMC article.

5

Hepatic Enzymes Relevant to the Disposition of (-)-∆⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC.

Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2019 Mar;47(3):249-256. doi: 10.1124/dmd.118.085548. Epub 2018 Dec 19. Drug Metab Dispos. 2019. PMID: 30567877 Free PMC article.

6

Quantifying Hepatic Enzyme Kinetics of (-)-∆⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC, through In Vitro Modeling.

Patilea-Vrana GI, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2019 Jul;47(7):743-752. doi: 10.1124/dmd.119.086470. Epub 2019 May 2. Drug Metab Dispos. 2019. PMID: 31048453 Free PMC article.

7

Development and Verification of a Linked Δ ⁹-THC/11-OH-THC Physiologically Based Pharmacokinetic Model in Healthy, Nonpregnant Population and Extrapolation to Pregnant Women.

Patilea-Vrana GI, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2021 Jul;49(7):509-520. doi: 10.1124/dmd.120.000322. Epub 2021 May 5. Drug Metab Dispos. 2021. PMID: 33952608 Free PMC article.

8

When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interactions.

Patilea-Vrana GI, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2018 Nov;46(11):1487-1496. doi: 10.1124/dmd.118.081307. Epub 2018 Aug 16. Drug Metab Dispos. 2018. PMID: 30115647 Free PMC article.

9

Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model.

Patilea-Vrana G, Unadkat JD. Patilea-Vrana G, et al. Clin Pharmacol Ther. 2016 Nov;100(5):413-418. doi: 10.1002/cpt.437. Epub 2016 Aug 27. Clin Pharmacol Ther. 2016. PMID: 27448198 Free PMC article.

10

Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses.

Zhang Z, Imperial MZ, Patilea-Vrana GI, Wedagedera J, Gaohua L, Unadkat JD. Zhang Z, et al. Among authors: patilea vrana gi. Drug Metab Dispos. 2017 Aug;45(8):920-938. doi: 10.1124/dmd.117.075192. Epub 2017 Jun 6. Drug Metab Dispos. 2017. PMID: 28588050 Free PMC article.

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