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Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.
Taskar KS, Pilla Reddy V, Burt H, Posada MM, Varma M, Zheng M, Ullah M, Emami Riedmaier A, Umehara KI, Snoeys J, Nakakariya M, Chu X, Beneton M, Chen Y, Huth F, Narayanan R, Mukherjee D, Dixit V, Sugiyama Y, Neuhoff S. Taskar KS, et al. Among authors: posada mm. Clin Pharmacol Ther. 2020 May;107(5):1082-1115. doi: 10.1002/cpt.1693. Epub 2019 Dec 31. Clin Pharmacol Ther. 2020. PMID: 31628859 Free PMC article. Review.
Prediction of Transporter-Mediated Drug-Drug Interactions for Baricitinib.
Posada MM, Cannady EA, Payne CD, Zhang X, Bacon JA, Pak YA, Higgins JW, Shahri N, Hall SD, Hillgren KM. Posada MM, et al. Clin Transl Sci. 2017 Nov;10(6):509-519. doi: 10.1111/cts.12486. Epub 2017 Jul 27. Clin Transl Sci. 2017. PMID: 28749581 Free PMC article. Clinical Trial.
Physiologically-Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid-to-Lactone Conversion.
Morse BL, Alberts JJ, Posada MM, Rehmel J, Kolur A, Tham LS, Loghin C, Hillgren KM, Hall SD, Dickinson GL. Morse BL, et al. Among authors: posada mm. CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):664-675. doi: 10.1002/psp4.12447. Epub 2019 Aug 1. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31250974 Free PMC article.
15 results