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Page 1
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels.
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JM, de Oliveira GC, Gomez LS, Hogan KA, Tarragó MG, Puranik AS, Agorrody G, Thompson KL, Dang K, Clarke S, Childs BG, Kanamori KS, Witte MA, Vidal P, Kirkland AL, De Cecco M, Chellappa K, McReynolds MR, Jankowski C, Tchkonia T, Kirkland JL, Sedivy JM, van Deursen JM, Baker DJ, van Schooten W, Rabinowitz JD, Baur JA, Chini EN. Chini CCS, et al. Among authors: tarrago mg. Nat Metab. 2020 Nov;2(11):1284-1304. doi: 10.1038/s42255-020-00298-z. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199925 Free PMC article.
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline.
Tarragó MG, Chini CCS, Kanamori KS, Warner GM, Caride A, de Oliveira GC, Rud M, Samani A, Hein KZ, Huang R, Jurk D, Cho DS, Boslett JJ, Miller JD, Zweier JL, Passos JF, Doles JD, Becherer DJ, Chini EN. Tarragó MG, et al. Cell Metab. 2018 May 1;27(5):1081-1095.e10. doi: 10.1016/j.cmet.2018.03.016. Cell Metab. 2018. PMID: 29719225 Free PMC article.
CD38-NADase is a new major contributor to Duchenne muscular dystrophic phenotype.
de Zélicourt A, Fayssoil A, Dakouane-Giudicelli M, De Jesus I, Karoui A, Zarrouki F, Lefebvre F, Mansart A, Launay JM, Piquereau J, Tarragó MG, Bonay M, Forand A, Moog S, Piétri-Rouxel F, Brisebard E, Chini CCS, Kashyap S, Fogarty MJ, Sieck GC, Mericskay M, Chini EN, Gomez AM, Cancela JM, de la Porte S. de Zélicourt A, et al. Among authors: tarrago mg. EMBO Mol Med. 2022 May 9;14(5):e12860. doi: 10.15252/emmm.202012860. Epub 2022 Mar 17. EMBO Mol Med. 2022. PMID: 35298089 Free PMC article.
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.
Zhang Y, Hao J, Tarrago MG, Warner GM, Giorgadze N, Wei Q, Huang Y, He K, Chen C, Peclat TR, White TA, Ling K, Tchkonia T, Kirkland JL, Chini EN, Hu J. Zhang Y, et al. Among authors: tarrago mg. Cell Rep. 2021 Aug 3;36(5):109481. doi: 10.1016/j.celrep.2021.109481. Cell Rep. 2021. PMID: 34348145 Free PMC article.
Surface color spectrophotometry in a murine model of steatosis: an accurate technique with potential applicability in liver procurement.
Kanamori KS, Tarragó MG, Jones A, Cheek EH, Warner GM, Jenkins SM, Povero D, Graham RP, Mounajjed T, Chedid MF, Sabat BD, Torbenson MS, Heimbach JK, Chini EN, Moreira RK. Kanamori KS, et al. Among authors: tarrago mg. Lab Invest. 2021 Aug;101(8):1098-1109. doi: 10.1038/s41374-021-00600-x. Epub 2021 Apr 15. Lab Invest. 2021. PMID: 33859335 Free article.
The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline.
Chini C, Hogan KA, Warner GM, Tarragó MG, Peclat TR, Tchkonia T, Kirkland JL, Chini E. Chini C, et al. Among authors: tarrago mg. Biochem Biophys Res Commun. 2019 May 28;513(2):486-493. doi: 10.1016/j.bbrc.2019.03.199. Epub 2019 Apr 8. Biochem Biophys Res Commun. 2019. PMID: 30975470 Free PMC article.