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Year | Number of Results |
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Page 1
Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability.
Bioorg Med Chem. 2006 Oct 15;14(20):6900-16. doi: 10.1016/j.bmc.2006.06.040. Epub 2006 Jul 25.
Bioorg Med Chem. 2006.
PMID: 16870455
10-Hydroxy-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-diones: potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants.
Wiscount CM, Williams PD, Tran LO, Embrey MW, Fisher TE, Sherman V, Homnick CF, Donnette Staas D, Lyle TA, Wai JS, Vacca JP, Wang Z, Felock PJ, Stillmock KA, Witmer MV, Miller MD, Hazuda DJ, Day AM, Gabryelski LJ, Ecto LT, Schleif WA, DiStefano DJ, Kochansky CJ, Anari MR.
Wiscount CM, et al. Among authors: tran lo.
Bioorg Med Chem Lett. 2008 Aug 15;18(16):4581-3. doi: 10.1016/j.bmcl.2008.07.037. Epub 2008 Jul 15.
Bioorg Med Chem Lett. 2008.
PMID: 18657970
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4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells.
Wai JS, Egbertson MS, Payne LS, Fisher TE, Embrey MW, Tran LO, Melamed JY, Langford HM, Guare JP Jr, Zhuang L, Grey VE, Vacca JP, Holloway MK, Naylor-Olsen AM, Hazuda DJ, Felock PJ, Wolfe AL, Stillmock KA, Schleif WA, Gabryelski LJ, Young SD.
Wai JS, et al. Among authors: tran lo.
J Med Chem. 2000 Dec 28;43(26):4923-6. doi: 10.1021/jm000176b.
J Med Chem. 2000.
PMID: 11150161
No abstract available.
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L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase.
Young SD, Britcher SF, Tran LO, Payne LS, Lumma WC, Lyle TA, Huff JR, Anderson PS, Olsen DB, Carroll SS, et al.
Young SD, et al. Among authors: tran lo.
Antimicrob Agents Chemother. 1995 Dec;39(12):2602-5. doi: 10.1128/AAC.39.12.2602.
Antimicrob Agents Chemother. 1995.
PMID: 8592986
Free PMC article.
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Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells.
Prueksaritanont T, Gorham LM, Hochman JH, Tran LO, Vyas KP.
Prueksaritanont T, et al. Among authors: tran lo.
Drug Metab Dispos. 1996 Jun;24(6):634-42.
Drug Metab Dispos. 1996.
PMID: 8781778
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