Substituted IV-aryl cyclic amineoxides undergo novel thermal rearrangement to O-arylhydroxylamines.
Electron-withdrawing substituents are essential for the rearrangement and must …

The formation of cytochrome P-450 metabolic intermediary (MI) complexes from a
homologous series of alpha-substituted 2-phenylethylamines and corresponding N-hydroxylamines …

While many studies relating to “C NMR of piperidine bases have been carried out [l-4], few
data [5-73 for their N-oxides have been reported although N-oxides sometimes appear as …

(4-Substituted-phenyl) piperidine N-oxides undergo a thermal rearrangementto O-arylhydroxylamines.
Electron-withdrawing substituents are essential for the rearrangementand must …

… Lindeke arbr *1 , AH Khuthier c) , MA Al-Iraqi c) a) Department of Organic Pharmaceutical
Chemistry Biomedical Center, University of Uppsala S-751 23 Uppsala, Sweden b) Kabl AB …

Pargyline undergoes metabolic N-oxidation in rat and rabbit liver microsomal preparations.
The reaction requires oxygen and is NADPH dependent. N-oxidation and N-demethylation …

Rearrangement of N-prop-2-ynylpiperidine N-oxide and N-prop-2-ynylmorpholine N-oxide
to the corresponding O-allenyl hydroxylamines is reported; this rearrangement appears to …

Carbon‐13 NMR chemical shifts and 1 J(CH), 2 J(CH) and 3 J(CH) coupling constants of
selected saturated nitrogen heterocyclic molecules containing the acetylenic moiety have been …

Results Reaction in Hydrochloric Acid.—The reaction of 1 with an equimolar quantity of
sodium azide in concen-trated HC1 producedonly 8, 9-dihydrophthalimidine (4) in 66% yield, …

Sixteen acetylenic amine oxides (5a–p) were prepared by the oxidation of the corresponding
tertiary amines (4a–p) with m‐chloroperbenzoic acid. The N‐oxides are thermally unstable …