The extent and nature of furosemide (F) binding to human albumin (HA) and to the plasma of
6 children with nephrotic syndrome were studied by equilibrium dialysis at 37 C and pH 7.4 …

Twenty preterm infants recovering from respiratory distress syndrome at 1 week of age were
randomized in this study either to a control or a treatment group. Those treated received a …

The renal clearance of furosemide and tetraethylammonium (TEA) were compared in 10
patients with hypertensive nephropathy. BUN and creatinine ranges were 10 to 88 mg/dl and …

Pharmacokinetic studies in 4 children with hypo glycemia who required diazoxide therapy
revealed a half‐life of the drug in blood of 9.5 to 24 hmlrs. The blood level of diazoxide in …

Triamterene is a pteridine used therapeutically as a diuretic. In order to better understand
variations in effect and toxicity of triamterene in individuals, the fate of the drug in man was …

… to adult plasma (Pruitt and Dayton, 1971) . Studies in cimildren … drug (Pruitt et at., 1973)
. In this report we present … drug were similar in rats and dogs (Pruitt et al., 1973). In vitro …

Systolic time intervals (STI) and serum digoxin concentrations (SDC) were measured in eight
patients with compensated atherosclerotic and/or hypertensive heart disease who received …

We modified the micro-scale spectrophotofluorometric method of Miceli et al. [Biochem. Med.
12, 348 (1975)] for the assay of "apparent" isoniazid (isoniazid plus acid-labile hydrazones) …

The relationship of natriuretic effect and furosemide excretion was studied in normal and
azotemic dogs. Graded azotemia was produced in dogs by bilateral uretero-venous shunts of …

Six cases of toxic ingestion of clonidine hydrochloride are reviewed. Apnea, respiratory
depression, and rhythm disturbances were more frequent in our patients than in those previously …