This study was undertaken to examine the influence of changes in dietary carbohydrate and
protein content on the oxidation of antipyrine and theophylline in man. When the diets of 6 …

The CO-difference spectrum of microsomes from rats treated with the polychlorinated biphenyls
mixture, Aroclor 1254, has an absorption maximum at 448 nm. With ethylisocyananide …

Eight healthy volunteers were sequentially fed a control diet, a charcoal‐broiled beef‐containing
diet, and the control diet a second time. The mean plasma half‐lives (t ½ ) of antipyrine …

The ability of honeybee venom to suppress Mycobacterium butyricum-induced arthritis was
studied in Lewis rats. Bee venom, 2mg · kg −1 · day −1 for 24 days, suppressed but did not …

Drug‐metabolizing capacities were determined in 10 normal adults and 10 children in the age
range from 1 to 8 years. Among the latter, 2 were normal and 8 had biochemical evidence …

This study was undertaken to examine the influence of nutritional factors on the activity of
the mixed function oxidase system in man, which is cytochrome P-450 dependent. Three …

The rat liver mixed function oxidase system which is responsible for the metabolism of
endogenous and exogenous compounds has been shown to be affected by lead and methyl …

Two-substrate kinetics was employed to show that more than one microsomal system functions
in the dealkylation of drugs. Evidence is also presented to show that in some dealkylation …

The polychlorinated biphenyl mixture, Aroclor 1254, is a powerful inducer of both cytochromes
P-450 and P-448 exhibiting the catalytic properties of both cytochromes in the liver. …

Liver microsomes and partially purified cytochromes P 450 prepared from untreated animals
or those injected with phenobarbital, or 3-methylcholanthrene, or polychlorinated biphenyls, …