Norbuprenorphine is a major metabolite of buprenorphine and potent agonist of μ, δ, and κ
opioid receptors. Compared with buprenorphine, norbuprenorphine causes minimal …

The long-acting opioid methadone displays considerable unexplained interindividual
pharmacokinetic variability. Methadone metabolism clinically occurs primarily by N-demethylation …

Bupropion hydroxylation is a bioactivation and metabolic pathway, and the standard clinical
CYP2B6 probe. This investigation determined the influence of CYP2B6 allelic variants on …

Drug interactions involving methadone and/or HIV antiretrovirals can be problematic.
Mechanisms whereby antiretrovirals induce clinical methadone clearance are poorly understood. …

BACKGROUND: There is considerable interindividual and intraindividual variability in
methadone metabolism and clearance. Methadone dosing is particularly challenging during …

In liquefied natural gas (LNG) plants and nitrogen rejections units (NRU) that utilize
aluminum heat exchangers, mercury (Hg) contaminates can result in corrosion of equipment, …

In liquefied natural gas (LNG) plants and nitrogen rejections units (NRU) that utilize
aluminum heat exchangers, mercury (Hg) contaminates can result in corrosion of equipment, …

… A special note of appreciation goes to Amanda Crafford for introducing me to the world of
ICP-MS. I thank her for her patience and effort during the training. This project could not have …

… I would like to thank Amanda Crafford for her constant reminder that life existed beyond
the lab and many good memories I will take away with me. I would like to thank Dr. Geetha …

The analysis of large molecules, especially biomolecules,(eg, proteins, DNA) benefits
greatly from the use of time-of-flight mass spectrometry (TOF-MS) and surface-induced …