A primate subfamily of galectins expressed at the maternal–fetal interface that promote immune cell death

…, R Romero, M Goodman, A Weckle… - Proceedings of the …, 2009 - National Acad Sciences
Galectins are proteins that regulate immune responses through the recognition of cell-surface
glycans. We present evidence that 16 human galectin genes are expressed at the maternal…

Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre-and postnatal human liver

Z Duanmu, A Weckle, SB Koukouritaki, RN Hines… - … of Pharmacology and …, 2006 - ASPET
Aryl- (SULT1A1), estrogen- (SULT1E1), and hydroxysteroid- (SULT2A1) sulfotransferases (SULTs)
are active determinants of xenobiotic detoxication and hormone metabolism in the …

Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal–fetal immune tolerance

…, R Romero, O Erez, A Weckle… - Proceedings of the …, 2008 - National Acad Sciences
Galectin-1 is an anti-inflammatory lectin with pleiotropic regulatory functions at the
crossroads of innate and adaptive immunity. It is expressed in immune privileged sites and is …

The core transcriptome of mammalian placentas and the divergence of expression with placental shape

DL Armstrong, MR McGowen, A Weckle, P Pantham… - Placenta, 2017 - Elsevier
Introduction The placenta is arguably the most anatomically variable organ in mammals
even though its primary function is conserved. Method Using RNA-Seq, we measured the …

Genomic data reject the hypothesis of a prosimian primate clade

NM Jameson, ZC Hou, KN Sterner, A Weckle… - Journal of Human …, 2011 - Elsevier
The phylogenetic position of tarsiers within the primates has been a controversial subject for
over a century. Despite numerous morphological and molecular studies, there has been …

[HTML][HTML] Dynamic gene expression in the human cerebral cortex distinguishes children from adults

KN Sterner, A Weckle, HT Chugani, AL Tarca… - PloS one, 2012 - journals.plos.org
In comparison with other primate species, humans have an extended juvenile period during
which the brain is more plastic. In the current study we sought to examine gene expression …

Ancient origin of placental expression in the growth hormone genes of anthropoid primates

…, NM Jameson, R Romero, AL Weckle… - Proceedings of the …, 2009 - National Acad Sciences
In anthropoid primates, growth hormone (GH) genes have undergone at least 2 independent
locus expansions, one in platyrrhines (New World monkeys) and another in catarrhines (…

Elephant transcriptome provides insights into the evolution of eutherian placentation

…, NG Than, JM Gonzalez, A Weckle… - Genome biology and …, 2012 - academic.oup.com
The chorioallantoic placenta connects mother and fetus in eutherian pregnancies. In order
to understand the evolution of the placenta and provide further understanding of placenta …

Rapid fractionation and isolation of whole blood components in samples obtained from a community-based setting

A Weckle, AE Aiello, M Uddin, S Galea… - JoVE (Journal of …, 2015 - jove.com
Collection and processing of whole blood samples in a non-clinical setting offers a unique
opportunity to evaluate community-dwelling individuals both with and without preexisting …

Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) in MCF10A breast …

RD Thomas, MR Green, C Wilson, AL Weckle… - Chemico-biological …, 2006 - Elsevier
The cytochrome P450 expression profile was determined in the MCF10A human breast
epithelial cell line, as was the ability of this cell line to catalyze the bioactivation of the cooked …