The drive for food is one of the most powerful of human and animal behaviors. Dopamine, a
neurotransmitter involved with motivation and reward, its believed to regulate food intake in …

We have investigated the binding of 123 I-labeled N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
(AM251), an analog of the …

Systemic acquired resistance (SAR), a highly desirable form of plant defense, provides
broad-spectrum immunity against diverse pathogens. The recent identification of seemingly …

This study examined the effect of the cannabinoid receptor agonist, WIN 55212-2, on the
electrically evoked release of [14C]acetylcholine (ACh) from superfused brain slices from the …

Priming is a major mechanism behind the immunological ‘memory’ observed during two key
plant systemic defences: systemic acquired resistance (SAR) and induced systemic …

The binding of [ 123 I]AM251 (a radioiodinated analog of the cannabinoid CB1 receptor
antagonist SR141716A) was compared to that of [ 3 H]CP 55,940 in mouse and rat brain …

Objectives: Recent studies using positron emission tomography (PET) have established the
relationship between an intravenous dose of cocaine and the percentage occupancy of the …

The reinforcing effects of cocaine and methylphenidate have been linked to their ability to
block dopamine transporters (DAT). Using positron emission tomography (PET), we previously …

The major active ingredient of marijuana, (−)‐Δ 9 ‐tetrahydrocannabinol, exerts its psychoactive
effects via binding to cannabinoid CB1 receptors, which are widely distributed in the …

The receptor occupancy required to produce cannabinoid effects in the central nervous system
was determined in both a neurochemical and a behavioral assay for cannabinoid actions…