User profiles for Andrzej T. Slominski
Andrzej SlominskiProfessor of Dermatology, UAB Verified email at uabmc.edu Cited by 42556 |
[BOOK][B] Melatoninergic system in the skin
…, B Zbytek, RM Slominski, JD Steketee, AT Slominski… - 2012 - Springer
Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et al. …
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et al. …
Melatonin membrane receptors in peripheral tissues: distribution and functions
RM Slominski, RJ Reiter… - Molecular and cellular …, 2012 - Elsevier
Many of melatonin’s actions are mediated through interaction with the G-protein coupled
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or, …
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or, …
[HTML][HTML] Melanoma, melanin, and melanogenesis: The Yin and Yang relationship
Melanin pigment plays a critical role in the protection against the harmful effects of ultraviolet
radiation and other environmental stressors. It is produced by the enzymatic transformation …
radiation and other environmental stressors. It is produced by the enzymatic transformation …
Key role of CRF in the skin stress response system
AT Slominski, MA Zmijewski, B Zbytek… - Endocrine …, 2013 - academic.oup.com
The discovery of corticotropin-releasing factor (CRF) or CRH defining the upper regulatory
arm of the hypothalamic-pituitary-adrenal (HPA) axis, along with the identification of the …
arm of the hypothalamic-pituitary-adrenal (HPA) axis, along with the identification of the …
How UV light touches the brain and endocrine system through skin, and why
The skin, a self-regulating protective barrier organ, is empowered with sensory and computing
capabilities to counteract the environmental stressors to maintain and restore disrupted …
capabilities to counteract the environmental stressors to maintain and restore disrupted …
[HTML][HTML] In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1
AT Slominski, TK Kim, HZ Shehabi, I Semak… - The FASEB …, 2012 - ncbi.nlm.nih.gov
We define previously unrecognized in vivo pathways of vitamin D 3 (D3) metabolism generating
novel D3-hydroxyderivatives different from 25-hydroxyvitamin D 3 [25 (OH) D3] and 1, …
novel D3-hydroxyderivatives different from 25-hydroxyvitamin D 3 [25 (OH) D3] and 1, …
[HTML][HTML] RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy-and 20, 23-dihydroxyvitamin D
AT Slominski, TK Kim, Y Takeda, Z Janjetovic… - The FASEB …, 2014 - ncbi.nlm.nih.gov
RORα and RORγ are expressed in human skin cells that produce the noncalcemic 20-hydroxyvitamin
D 3 [20 (OH) D 3] and 20, 23-dihydroxyvitamin D 3 [20, 23 (OH) 2 D 3]. Chinese …
D 3 [20 (OH) D 3] and 20, 23-dihydroxyvitamin D 3 [20, 23 (OH) 2 D 3]. Chinese …
Novel activities of CYP11A1 and their potential physiological significance
CYP11A1, found only in vertebrates, catalyzes the first step of steroidogenesis where
cholesterol is converted to pregnenolone. The purified enzyme, also converts desmosterol and …
cholesterol is converted to pregnenolone. The purified enzyme, also converts desmosterol and …
[HTML][HTML] Melatonin: a cutaneous perspective on its production, metabolism, and functions
AT Slominski, R Hardeland, MA Zmijewski… - Journal of Investigative …, 2018 - Elsevier
Melatonin, an evolutionarily ancient derivative of serotonin with hormonal properties, is the
main neuroendocrine secretory product of the pineal gland. Although melatonin is best …
main neuroendocrine secretory product of the pineal gland. Although melatonin is best …
Photobiology of vitamin D
MF Holick, AT Slominski - Feldman and Pike's Vitamin D, 2024 - Elsevier
Vitamin D is the sunshine vitamin. During exposure to sunlight, 7-dehydrocholesterol in the
skin absorbs ultraviolet B (UVB) radiation converting it to previtamin D3. Previtamin D3 being …
skin absorbs ultraviolet B (UVB) radiation converting it to previtamin D3. Previtamin D3 being …