User profiles for Arul Jayaraman
Arul JayaramanProfessor of Chemical Engineering, Texas A&M University Verified email at tamu.edu Cited by 11558 |
The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation
…, TK Wood, A Jayaraman - Proceedings of the …, 2010 - National Acad Sciences
Interkingdom signaling is established in the gastrointestinal tract in that human hormones
trigger responses in bacteria; here, we show that the corollary is true, that a specific bacterial …
trigger responses in bacteria; here, we show that the corollary is true, that a specific bacterial …
[HTML][HTML] Indole is an inter-species biofilm signal mediated by SdiA
Background As a stationary phase signal, indole is secreted in large quantities into rich medium
by Escherichia coli and has been shown to control several genes (eg, astD, tnaB, gabT), …
by Escherichia coli and has been shown to control several genes (eg, astD, tnaB, gabT), …
Bacterial quorum sensing: signals, circuits, and implications for biofilms and disease
A Jayaraman, TK Wood - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
Communication between bacteria, belonging to the same species or to different species, is
mediated through different chemical signals that are synthesized and secreted by bacteria. …
mediated through different chemical signals that are synthesized and secreted by bacteria. …
[PDF][PDF] Gut microbiota-derived tryptophan metabolites modulate inflammatory response in hepatocytes and macrophages
The gut microbiota plays a significant role in the progression of fatty liver disease; however,
the mediators and their mechanisms remain to be elucidated. Comparing metabolite profile …
the mediators and their mechanisms remain to be elucidated. Comparing metabolite profile …
Differential Effects of Epinephrine, Norepinephrine, and Indole on Escherichia coli O157:H7 Chemotaxis, Colonization, and Gene Expression
During infection in the gastrointestinal tract, enterohemorrhagic Escherichia coli (EHEC)
O157:H7 is exposed to a wide range of signaling molecules, including the eukaryotic hormones …
O157:H7 is exposed to a wide range of signaling molecules, including the eukaryotic hormones …
Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities
The tryptophan metabolites indole, indole-3-acetate, and tryptamine were identified in mouse
cecal extracts and fecal pellets by mass spectrometry. The aryl hydrocarbon receptor (AHR…
cecal extracts and fecal pellets by mass spectrometry. The aryl hydrocarbon receptor (AHR…
[HTML][HTML] Prediction and quantification of bioactive microbiota metabolites in the mouse gut
…, RC Alaniz, K Lee, A Jayaraman - Nature …, 2014 - nature.com
Metabolites produced by the intestinal microbiota are potentially important physiological
modulators. Here we present a metabolomics strategy that models microbiota metabolism as a …
modulators. Here we present a metabolomics strategy that models microbiota metabolism as a …
Enterohemorrhagic Escherichia coli Biofilms Are Inhibited by 7-Hydroxyindole and Stimulated by Isatin
Since indole is present at up to 500 μM in the stationary phase and is an interspecies biofilm
signal (J. Lee, A. Jayaraman, and TK Wood, BMC Microbiol. 7:42, 2007), we investigated …
signal (J. Lee, A. Jayaraman, and TK Wood, BMC Microbiol. 7:42, 2007), we investigated …
A high-throughput microfluidic real-time gene expression living cell array
The dynamics of gene expression are fundamental to the coordination of cellular responses.
Measurement of temporal gene expression patterns is currently limited to destructive low-…
Measurement of temporal gene expression patterns is currently limited to destructive low-…
[HTML][HTML] Synthetic quorum-sensing circuit to control consortial biofilm formation and dispersal in a microfluidic device
To utilize biofilms for chemical transformations in biorefineries they need to be controlled
and replaced. Previously, we engineered the global regulator Hha and cyclic diguanylate-…
and replaced. Previously, we engineered the global regulator Hha and cyclic diguanylate-…