Cytochrome P450-dependent metabolism in HepaRG cells cultured in a dynamic three-dimensional bioreactor
…, T Urbaniak, T Söderdahl, I Rossberg, B Dillnér… - Drug Metabolism and …, 2011 - ASPET
Reliable and stable in vitro cellular systems maintaining specific liver functions important for
drug metabolism and disposition are urgently needed in preclinical drug discovery and …
drug metabolism and disposition are urgently needed in preclinical drug discovery and …
Evaluation of organic anion-transporting polypeptide 1B1 and CYP3A4 activities in primary human hepatocytes and HepaRG cells cultured in a dynamic three …
The long-term stability of liver cell functions is a major challenge when studying hepatic drug
transport, metabolism, and toxicity in vitro. The aim of the present study was to investigate …
transport, metabolism, and toxicity in vitro. The aim of the present study was to investigate …
[CITATION][C] Drug Metabolism and Disposition
…, T Urbaniak, T Söderdahl, I Rossberg, B Dillnér… - 1986 - ASPET