Chronic, low-level oral exposure to marine toxin, domoic acid, alters whole brain morphometry in nonhuman primates
R Petroff, T Richards, B Crouthamel, N McKain… - Neurotoxicology, 2019 - Elsevier
Domoic acid (DA) is an excitatory neurotoxin produced by marine algae and responsible for
Amnesiac Shellfish Poisoning in humans. Current regulatory limits (0.075-0.1 mg/kg/day) …
Amnesiac Shellfish Poisoning in humans. Current regulatory limits (0.075-0.1 mg/kg/day) …
Toxicokinetics and physiologically based pharmacokinetic modeling of the shellfish toxin domoic acid in nonhuman primates
J Jing, R Petroff, S Shum, B Crouthamel… - Drug Metabolism and …, 2018 - ASPET
Domoic acid (DA), a neurotoxin, is produced by marine algae and has caused toxications
worldwide in animals and humans. However, the toxicokinetics of DA have not been fully …
worldwide in animals and humans. However, the toxicokinetics of DA have not been fully …
Effects of oral domoic acid exposure on maternal reproduction and infant birth characteristics in a preclinical nonhuman primate model
…, KS Grant, R Petroff, S Shum, B Crouthamel… - Neurotoxicology and …, 2019 - Elsevier
Domoic Acid (DA) is a naturally-occurring excitotoxin, produced by marine algae, which can
bioaccumulate in shellfish and finfish. The consumption of seafood contaminated with DA is …
bioaccumulate in shellfish and finfish. The consumption of seafood contaminated with DA is …
Preclinical modeling of exposure to a global marine bio-contaminant: Effects of in utero Domoic acid exposure on neonatal behavior and infant memory
KS Grant, B Crouthamel, C Kenney, N McKain… - Neurotoxicology and …, 2019 - Elsevier
Domoic Acid (DA) is a naturally-occurring marine neurotoxin that is increasingly recognized
as an important public health issue. Prenatal DA exposure occurs through the maternal …
as an important public health issue. Prenatal DA exposure occurs through the maternal …
Validated HPLC-MS/MS method to quantify low levels of domoic acid in plasma and urine after subacute exposure
…, JS Kirkwood, J Jing, R Petroff, B Crouthamel… - ACS …, 2018 - ACS Publications
Domoic acid (DA) is a marine neurotoxin produced by several species of Pseudo-nitzschia.
DA causes severe neurological toxicity in humans and animals. To address the current …
DA causes severe neurological toxicity in humans and animals. To address the current …
Maternal-fetal disposition of domoic acid following repeated oral dosing during pregnancy in nonhuman primate
S Shum, J Jing, R Petroff, B Crouthamel… - Toxicology and applied …, 2020 - Elsevier
Domoic acid (DA) is a marine algal toxin that causes acute and chronic neurotoxicity in animals
and humans. Prenatal exposure to DA has been associated with neuronal damage and …
and humans. Prenatal exposure to DA has been associated with neuronal damage and …
Some effects of risperidone and quetiapine on growth parameters and hormone levels in young pigtail macaques
G Sackett, A Unis, B Crouthamel - Journal of Child and Adolescent …, 2010 - liebertpub.com
Objective: Atypical antipsychotic drugs are prescribed to young children for a number of
symptoms, some with no Food and Drug Administration approval for children. Effects on growth …
symptoms, some with no Food and Drug Administration approval for children. Effects on growth …
Prolonged, low-level exposure to the marine toxin, domoic acid, and measures of neurotoxicity in nonhuman primates
…, J Jing, N Isoherranen, B Crouthamel… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: The excitotoxic molecule, domoic acid (DA), is a marine algal toxin known to
induce overt hippocampal neurotoxicity. Recent experimental and epidemiological studies …
induce overt hippocampal neurotoxicity. Recent experimental and epidemiological studies …
[PDF][PDF] Oral medication administration: Training monkeys to take juice from a syringe
B Crouthamel, G Sackett - Laboratory Primate Newsletter43, 2004 - Citeseer
Many research projects and some clinical procedures require repeated daily doses of
medications over many days, weeks, or months. Administration can often be done by mouth or by …
medications over many days, weeks, or months. Administration can often be done by mouth or by …
Maternal‐Fetal Toxicokinetics of the Shellfish Toxin Domoic Acid
S Shum, KS Grant, R Petroff, B Crouthamel… - The FASEB …, 2018 - Wiley Online Library
Background Domoic Acid (DA) is an excitatory neurotoxin produced by harmful algal blooms.
Through the marine food web, humans and marine mammals can be exposed to DA and …
Through the marine food web, humans and marine mammals can be exposed to DA and …