Prevalence of prostate cancer on autopsy: cross-sectional study on unscreened Caucasian and Asian men

…, T Kimura, M Kido, H Takahashi, C Kuk… - Journal of the …, 2013 - academic.oup.com
Background Substantial geographical differences in prostate cancer (PCa) incidence and
mortality exist, being lower among Asian (ASI) men compared with Caucasian (CAU) men. We …

Propensity score analysis of radical cystectomy versus bladder-sparing trimodal therapy in the setting of a multidisciplinary bladder cancer clinic

…, P Athanasopoulos, PJ Bostrom, C Kuk… - Journal of clinical …, 2017 - zora.uzh.ch
Purpose Multidisciplinary management improves complex treatment decision making in
cancer care, but its impact for bladder cancer (BC) has not been documented. Although radical …

Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients

N Komatsu, K Saijoh, C Kuk, AC Liu… - Experimental …, 2007 - Wiley Online Library
Human tissue kallikreins are a family of 15 trypsin‐ or chymotrypsin‐like secreted serine
proteases (KLK1–KLK15). Many KLKs have been identified in normal stratum corneum (SC) …

[HTML][HTML] Mining the Ovarian Cancer Ascites Proteome for Potential Ovarian Cancer Biomarkers* S

C Kuk, V Kulasingam, CG Gunawardana… - Molecular & Cellular …, 2009 - ASBMB
Current ovarian cancer biomarkers are inadequate because of their relatively low diagnostic
sensitivity and specificity. There is a need to discover and validate novel ovarian cancer …

Loss of androgen receptor expression is not associated with pathological stage, grade, gender or outcome in bladder cancer: a large multi‐institutional study

…, S Skeldon, S Hanna, R Vajpeyi, C Kuk… - BJU …, 2011 - Wiley Online Library
… The buffer was brought to a temperature of 95 C and timed for 40 min. Sections were then
… of high pH (EDTA) buffer for 20 min at 99 C with a brief cool down period. Slides were then …

Upstaging of urothelial cancer at the time of radical cystectomy: factors associated with upstaging and its effect on outcome

…, B van Rhijn, H Kortekangas, C Kuk… - BJU …, 2012 - Wiley Online Library
… Cynthia Kuk… Cynthia Kuk … OS and DSS rates in patients with clinical <cT2 (A and B)
and cT2 diseases (C and D) with and without upstaging from OC to nOC disease. …

Inhibition of IRF4 in dendritic cells by PRR-independent and-dependent signals inhibit Th2 and promote Th17 responses

J Lee, J Zhang, YJ Chung, JH Kim, CM Kook… - Elife, 2020 - elifesciences.org
Cyclic AMP (cAMP) is involved in many biological processes but little is known regarding its
role in shaping immunity. Here we show that cAMP-PKA-CREB signaling (a pattern …

Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy

N Komatsu, K Saijoh, C Kuk, F Shirasaki… - British Journal of …, 2007 - academic.oup.com
Background Human tissue kallikreins (KLKs) are a family of 15 trypsin‐like or chymotrypsin‐like
secreted serine proteases (KLK1–KLK15). Multiple KLKs have been quantitatively …

Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer

CG Gunawardana, C Kuk, CR Smith… - Journal of Proteome …, 2009 - ACS Publications
Ovarian cancer remains a deadly threat to women as the disease is often diagnosed in the
late stages when the chance of survival is low. There are no good biomarkers available for …

Upper urinary tract and urethral recurrences following radical cystectomy: review of risk factors and outcomes between centres with different follow-up protocols

N Perlis, P Turker, PJ Bostrom, C Kuk, T Mirtti… - World journal of …, 2013 - Springer
Purpose To examine which patient-related and tumour-related characteristics predict upper
urinary tract recurrence (UUTR) and urethral recurrence (UR) of bladder cancer post-radical …