Physiologically based pharmacokinetic modeling and simulation can be used to predict the
pharmacokinetics of drugs in human populations and to explore the effects of varying …

Several reports in the literature present the utility and value of in vitro drug-metabolizing
enzyme inhibition data to predict in vivo drug-drug interactions in humans. A retrospective …

Orally administered drugs are subject to a number of barriers impacting bioavailability (F
oral ), causing challenges during drug and formulation development. Physiologically-based …

… 9E). This underprediction of F oral for low permeable compounds could potentially indicate
an oversensitivity of the models to in vitro permeability measurements, improper intestinal …

Fabry disease is an X-linked lysosomal storage disorder caused by mutations in the gene
that encodes α-galactosidase A and is characterized by pathological accumulation of …

… Steven Shardlow. These qualitative studies were carried out by a team which also included
… Hugh McLaughlin and Steven Shardlow on the qualitative case and organisational studies. …

… Paul needs trees in a bad way—if you check out maps of the urban heat island in our city,
you can see it,” said project lead er Ben Shardlow, CEZ vice chair. “We hope to use what we …

… John Carpenter took the lead in writing the evaluation reports, with substantial contributions
from Demi Patsios, Marsha Wood on the survey data and from Steven Shardlow on the …

… Steven Shardlow. These qualitative studies were carried out by a team which also included
… Hugh McLaughlin and Steven Shardlow on the qualitative case and organisational studies. …

This substantially revised, expanded and updated edition of the popular Handbook of Theory
for Practice Teachers is a comprehensive summary of the theory, knowledge, research and …