User profiles for Caroline Keller

Caroline Keller

- Verified email at sorbonne-universite.fr - Cited by 154

Caroline K. Keller

- Verified email at ucdavis.edu - Cited by 48

SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

…, M Van Hoosear, Y Shin, DN Chin, CG Keller… - Nature chemical …, 2015 - nature.com
Spinal muscular atrophy (SMA), which results from the loss of expression of the survival of
motor neuron-1 (SMN1) gene, represents the most common genetic cause of pediatric …

Scalable chemical synthesis of doped silicon nanowires for energy applications

O Burchak, C Keller, G Lapertot, M Salaün, J Danet… - Nanoscale, 2019 - pubs.rsc.org
A versatile, low-cost and easily scalable synthesis method is presented for producing silicon
nanowires (SiNWs) as a pure powder. It applies air-stable diphenylsilane as a Si source …

[HTML][HTML] An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion

CG Keller, Y Shin, AM Monteys, N Renaud… - Nature …, 2022 - nature.com
Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by CAG
trinucleotide repeat expansions in exon 1 of the huntingtin (HTT) gene. The mutant HTT (mHTT) …

[HTML][HTML] DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

…, S Renner, R Ihry, L Mansur, CG Keller… - Nature …, 2018 - nature.com
Here we report Digital RNA with pertUrbation of Genes (DRUG-seq), a high-throughput
platform for drug discovery. Pharmaceutical discovery relies on high-throughput screening, yet …

[PDF][PDF] Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine

…, HJ Dean, R Lorenzo-Redondo, M Stewart, CK Keller… - Cell reports, 2022 - cell.com
The tetravalent dengue vaccine candidate, TAK-003, induces a functional antibody response,
but the titers of antibodies against the four serotypes of the dengue virus (DENV) can vary. …

[PDF][PDF] YAP, but not RSPO-LGR4/5, signaling in biliary epithelial cells promotes a ductular reaction in response to liver injury

…, LM Terracciano, C Russ, JS Reece-Hoyes, CG Keller… - Cell stem cell, 2019 - cell.com
Biliary epithelial cells (BECs) form bile ducts in the liver and are facultative liver stem cells
that establish a ductular reaction (DR) to support liver regeneration following injury. Liver …

A scalable silicon nanowires-grown-on-graphite composite for high-energy lithium batteries

S Karuppiah, C Keller, P Kumar, PH Jouneau… - ACS …, 2020 - ACS Publications
Silicon (Si) is the most promising anode candidate for the next generation of lithium-ion
batteries but difficult to cycle due to its poor electronic conductivity and large volume change …

[HTML][HTML] Effect of size and shape on electrochemical performance of nano-silicon-based lithium battery

C Keller, A Desrues, S Karuppiah, E Martin, JP Alper… - Nanomaterials, 2021 - mdpi.com
Silicon is a promising material for high-energy anode materials for the next generation of
lithium-ion batteries. The gain in specific capacity depends highly on the quality of the Si …

[HTML][HTML] Recurrent miscarriages and the association with regulatory T cells; A systematic review

CC Keller, M Eikmans, MLP van der Hoorn… - Journal of reproductive …, 2020 - Elsevier
Regulatory T cells (Tregs) are essential in tolerizing the maternal immune system toward the
semi-allogeneic embryo. In this systematic review, we evaluated the association of levels …

Genetic variation underlying differential ammonium and nitrate responses in Arabidopsis thaliana

E Katz, A Knapp, M Lensink, CK Keller, J Stefani… - The Plant …, 2022 - academic.oup.com
Nitrogen is an essential element required for plant growth and productivity. Understanding
the mechanisms and natural genetic variation underlying nitrogen use in plants will facilitate …