Curcumin, a major component of the Curcuma species, is known to have antioxidant, anti-inflammatory
properties and induce apoptosis of cancer cells, however, the precise molecular …

Highly lipophilic compounds are often encountered in the early stages of drug discovery. The
apparent permeability (Papp) of these compounds in Caco-2 cell could be underestimated …

Evidence has accumulated that berberine is able to induce cell cycle arrest and apoptosis in
many human cancer cell lines. However, there is no available information on the effects of …

Baicalein was investigated for tumor cell-specific cytotoxicity, apoptosis-inducing activity
and signal pathway against the MDA-MB-231 human breast cancer cell line. After the MDA-MB-…

The objectives of this research were first to isolate plastid gene sequences from cabbage (Brassica
oleracea L. var. capitata L.), and to establish the chloroplast transformation …

Genistein, a major isoflavone compound in soybeans, has been shown to have biological
activities including anti‐cancer activates. In the present, we investigated the anti‐leukemia …

The aim of this study was to clarify the mechanisms of apoptosis, cytotoxicity, DNA damage
and fragmentation, as well as the production of reactive oxygen species (ROS) and Ca +2 , …

Berberine has a wide range of biological actions that suggest it may be of use in cancer
prevention. It was previously reported that berberine induced cell cycle arrest, not only at the G0/…

Wogonin (5, 7-dihydroxy-8-methoxyflavone) is a flavone constituent of Scutellaria
baicalensis with various beneficial biological activities and it has been shown to have tumor …

Temozolomide (SCH 52365; TEMODAL™) is an antineoplastic agent with activity against a
broad spectrum of murine tumors. This compound is currently marketed in the European …