Property-based design: optimization of drug absorption and pharmacokinetics

…, DA Smith, K Beaumont, DK Walker - Journal of medicinal …, 2001 - ACS Publications
Drugs may be administered via different routes, the oral route generally being the preferred
for reasons of ease and compliance by the patient. Absorption via these routes will take …

Recommendations for the implementation of distress screening programs in cancer centers: report from the American Psychosocial Oncology Society (APOS) …

…, M Lazenby, L Wagner, M Underhill, DK Walker… - Cancer, 2014 - Wiley Online Library
In 2015, the American College of Surgeons (ACoS) Commission on Cancer will require cancer
centers to implement screening programs for psychosocial distress as a new criterion for …

Design of drugs involving the concepts and theories of drug metabolism and pharmacokinetics.

DA Smith, BC Jones, DK Walker - Medicinal research reviews, 1996 - europepmc.org
Drug metabolism input to the discovery process had historically been on an empirical case-by-case
basis, since, detailed descriptors of the effect on pharmacokinetics of a change in …

Persons with disabilities as an unrecognized health disparity population

GL Krahn, DK Walker… - American journal of …, 2015 - ajph.aphapublications.org
Disability is an emerging field within public health; people with significant disabilities account
for more than 12% of the US population. Disparity status for this group would allow federal …

Chronic conditions, socioeconomic risks, and behavioral problems in children and adolescents

SL Gortmaker, DK Walker, M Weitzman, AM Sobol - Pediatrics, 1990 - publications.aap.org
Children with a chronic health condition have long been considered at excess risk for
psychosocial morbidity. Despite an increasing prevalence of chronic childhood conditions and …

Maternal smoking and childhood asthma

M Weitzman, S Gortmaker, DK Walker, A Sobol - Pediatrics, 1990 - publications.aap.org
According to a substantial literature, passive smoking by children is associated with an
increased incidence of lower respiratory illness and diminished pulmonary function. The …

Factors to consider when selecting a culture of Lactobacillus acidophilus as a dietary adjunct to produce a hypocholesterolemic effect in humans

SE Gilliland, DK Walker - Journal of dairy science, 1990 - Elsevier
Significant variations in bile tolerance and ability to assimilate cholesterol were observed
among 12 cultures of Lactobacillus acidophilus of human origin. The degree of bile tolerance …

Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man

DK Walker - Xenobiotica, 1999 - Taylor & Francis
1. Pharmacokinetics were studied in mouse, rat, rabbit, dog and man after single intravenous
and or oral doses of sildenafil or [ 14 C]-sildenafil (Viagra™). 2. In man, absorption from the …

Issues involved in the definition and classification of chronic health conditions

…, J Leventhal, JM Perrin, REK Stein, DK Walker… - …, 1993 - publications.aap.org
The need for a widely applicable definition of chronic conditions for research, policy, and
program development has led to an extensive review of the development of such definitions, …

Relationships among bile tolerance, bile salt deconjugation, and assimilation of cholesterol by Lactobacillus acidophilus

DK Walker, SE Gilliland - Journal of dairy science, 1993 - Elsevier
The relationships among growth in the presence of bile, deconjugation of sodium taurocholate,
and assimilation of cholesterol by 19 cultures of Lactobacillus acidophilus were examined…