Study Objective: To correlate oral ketoconazole absorption with gastric acid secretion in
patients with the acquired immunodeficiency syndrome (AIDS). Design: Prospective …

… First, it has significant affinity for the dopamine D 2 receptor in which it acts as an antagonist.
Second, it undergoes rapid first pass metabolism, giving it poor oral bioavailability. One of …

The effects of the dopamine D2 selective receptor antagonist, remoxipride, on dopamine
turnover in the rat brain were studied after acute and repeated administration and compared …

… Foscarnet was from Astra Alab AB and actinomycin D from Sigma. For synthesis of … activity
dependent on DNA template was blocked by actinomycin D at a final concentration of 100 pg/…

The acyclic guanosine analog (R,S)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine, (+/-)2HM-HBG,
is an effective inhibitor of herpes simplex virus and varicella-zoster virus infections in …

In an effort to improve the gastrointestinal absorption of (R,S)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine
[(+/-)2HM-HBG], various salts and esters of the compound were synthesized …

An iron carbohydrate complex, iron‐poly (sorbitol‐gluconic acid), Ferastral®, was labelled
with 59 Fe, and its distribution in rats was studied. The animals were intramuscularly treated …

… LakeBakaar 1977). The distribution and iron utilisation … administration (Lake-Bakaar &
Lindvall 1977; LakeBakaar 1980). … Lake-Bakaar DM: Disposition in rats of the carbohydrate …

Resistance mutations to hepatitis C virus (HCV) nonstructural protein 3 (NS3) protease
inhibitors in <1% of the viral quasispecies may still allow >1000‐fold viral load reductions upon …

The pharmacokinetics of the main metabolftes of cefcanel daloxate hydrochloride, a new oral
cephalosporin diester prodrug, was inves-tigated. Cefcanel is antimicrobially active. After …