Pharmacokinetics (PK), which describes the disposition of a drug in the body, should be a
primary consideration in the selection of a drug candidate, ultimately contributing to its …

Background This study examines the association of potentially inappropriate medication
prescribing (PIRx) with hospitalization and death among elderly long-stay nursing home …

OBJECTIVE—This study examines the association between oral antihyperglycemic medication
nonadherence and subsequent hospitalization among individuals with type 2 diabetes. …

Background & Aims: Therapy with interferon alfa (IFN- or death. Small follow-up studies10,
11 have reported that a) leads to remission of disease in one third of patients remissions in …

Background Serious safety concerns related to the use of antipsychotics have not decreased
the prescribing of these agents to nursing home (NH) residents. We assessed the extent to …

Background & Aims T cells play a critical role in viral infection. We examined whether T-cell
effector and regulatory responses can define clinical stages of chronic hepatitis B (CHB). …

… Dr Lau was supported by a K-01 career development award (5K01AG027295-02) from the
National … Dr Lau and Mr Mercaldo had full access to all of the data in the study and takes …

Sustained responses to interferon-α occur in 10% to 25% of patients with chronic hepatitis C,
but the long-term outcome is not well defined. We evaluated the long-term clinical, …

… Research was conducted when Denys Lau was a program analyst at the Center for Cost
and Financing Studies, Agency for Healthcare Research and Quality (AHRQ), Department of …

Chronic delta hepatitis is a severe form of chronic liver disease caused by hepatitis delta
virus (HDV) infection superimposed on chronic hepatitis B or the hepatitis B surface antigen (…