User profiles for David Goldman

David Goldman

Clinical Director, Chief, Lab of Neurogenetics
Verified email at mail.nih.gov
Cited by 72830

Potential, impedance, and rectification in membranes

DE Goldman - The Journal of general physiology, 1943 - rupress.org
Impedance and potential measurements have been made on a number of artificial membranes.
Impedance changes were determined as functions of current and of the composition of …

Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America

…, WE Dismukes, F Dromer, DL Goldman… - Clinical infectious …, 2010 - academic.oup.com
Cryptococcosis is a global invasive mycosis associated with significant morbidity and
mortality. These guidelines for its management have been built on the previous Infectious …

[HTML][HTML] The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

…, A Bertolino, E Zaitsev, B Gold, D Goldman… - Cell, 2003 - cell.com
Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity and
hippocampal-dependent memory in cell models and in animals. We examined the effects of a valine …

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

…, CM Mazzanti, RE Straub, D Goldman… - Proceedings of the …, 2001 - National Acad Sciences
Abnormalities of prefrontal cortical function are prominent features of schizophrenia and have
been associated with genetic risk, suggesting that susceptibility genes for schizophrenia …

Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins

CR Merril, D Goldman, SA Sedman, MH Ebert - Science, 1981 - science.org
A new silver stain for electrophoretically separated polypeptides can be rapidly and easily
used and can detect as little as 0.01 nanogram of protein per square millimeter. When …

Serotonin transporter genetic variation and the response of the human amygdala

…, A Tessitore, B Kolachana, F Fera, D Goldman… - Science, 2002 - science.org
A functional polymorphism in the promoter region of the human serotonin transporter gene (SLC6A4)
has been associated with several dimensions of neuroticism and psychopathology, …

[PDF][PDF] Dating the origin of the CCR5-Δ32 AIDS-resistance allele by the coalescence of haplotypes

…, V Baranov, H Sibul, A Metspalu, D Goldman… - The American Journal of …, 1998 - cell.com
The CCR5-Δ32 deletion obliterates the CCR5 chemokine and the human immunodeficiency
virus (HIV)–1 coreceptor on lymphoid cells, leading to strong resistance against HIV-1 …

Genetic basis for individual variations in pain perception and the development of a chronic pain condition

…, A Sigurdsson, I Belfer, D Goldman… - Human molecular …, 2005 - academic.oup.com
Pain sensitivity varies substantially among humans. A significant part of the human population
develops chronic pain conditions that are characterized by heightened pain sensitivity. …

COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor

…, K Xu, Y Xu, RA Koeppe, CS Stohler, D Goldman - Science, 2003 - science.org
Responses to pain and other stressors are regulated by interactions between multiple brain
areas and neurochemical systems. We examined the influence of a common functional …

[HTML][HTML] Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder

…, JL Kennedy, DL Murphy, D Goldman - The American Journal of …, 2006 - cell.com
A functional serotonin transporter promoter polymorphism, HTTLPR, alters the risk of disease
as well as brain morphometry and function. Here, we show that HTTLPR is functionally …