User profiles for David Hung

David Hung Wei Loong

Professor of Education, National Institute of Education
Verified email at nie.edu.sg
Cited by 5585

Situated cognition and problem-based learning: Implications for learning and instruction with technology

D Hung - Journal of interactive learning Research, 2002 - learntechlib.org
The aims of this article are three-fold. First, this article reviews the foundational premises of
situated cognition and attempts to substantiate its theoretical underpinnings with the …

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study

…, D Rathkopf, J Shelkey, YY Evan, J Alumkal, D Hung… - The Lancet, 2010 - thelancet.com
Background MDV3100 is an androgen-receptor antagonist that blocks androgens from binding
to the androgen receptor and prevents nuclear translocation and co-activator recruitment …

Situated cognition, Vygotskian thought and learning from the communities of practice perspective: Implications for the design of web-based e-learning

DWL Hung, DT Chen - Educational Media International, 2001 - Taylor & Francis
This paper describes the key notions of situated cognition, Vygotskian thought (zone of
proximal development, the general law of cultural development and the mediational nature of …

A review on the experimental non-intrusive investigation of fuel injector phase changing flow

S Yang, Z Ma, X Li, DLS Hung, M Xu - Fuel, 2020 - Elsevier
Two-phase in-nozzle flows, such as cavitation and flash boiling, have been well studied as
effective means to enhance spray breakup and atomization via phase change both within the …

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

TKH Vu, DT Hung, VI Wheaton, SR Coughlin - Cell, 1991 - cell.com
We isolated a cDNA encoding a functional human thrombin receptor by direct expression
cloning in Xenopus oocytes. mRNA encoding this receptor was detected in human platelets …

Development of a second-generation antiandrogen for treatment of advanced prostate cancer

…, D Welsbie, CD Chen, CS Higano, TM Beer, DT Hung… - Science, 2009 - science.org
Metastatic prostate cancer is treated with drugs that antagonize androgen action, but most
patients progress to a more aggressive form of the disease called castration-resistant prostate …

A review on the recent advances of flash boiling atomization and combustion applications

X Li, S Wang, S Yang, S Qiu, Z Sun, DLS Hung… - Progress in Energy and …, 2024 - Elsevier
Flash boiling atomization is a promising approach to enhance spray atomization with
internal energy as the driving force as well. Past investigations primarily focused on the …

Domains specifying thrombin–receptor interaction

TKH Vu, VI Wheaton, DT Hung, I Charo, SR Coughlin - Nature, 1991 - nature.com
PLATELET activation by the coagulation protease thrombin is central to arterial thrombosis,
a major cause of morbidity and mortality. We recently isolated a complementary DNA …

Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double …

…, RG Thomas, PS Aisen, SO Bachurin, L Seely, D Hung - The Lancet, 2008 - thelancet.com
Background Although treatments for Alzheimer's disease sometimes improve cognition,
functional ability, or behaviour compared with baseline levels, such improvements are …

Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR

…, N Sacchi, E Gabrielson, AB Soito, DT Hung… - The Lancet, 2001 - thelancet.com
If detected early, breast cancer is curable. We tested cells collected from the breast ducts by
methylation-specific PCR (MSP). Methylated alleles of Cyclin D2, RAR-β, and Twist genes …