In vivo delivery of siRNAs designed to inhibit genes important in cancer and other diseases
continues to be an important biomedical goal. A new nanoparticle construct that is …

Fibrotic diseases such as scleroderma have been linked to increased oxidative stress and
upregulation of pro-fibrotic genes. Recent work suggests a role of NADPH oxidase 4 (NOX4) …

Metastatic breast cancer is developed in about 20% to 30% of newly diagnosed patients
with early-stage breast cancer despite treatments. Herein, we report a novel nanoparticle …

Bell peppers are one of the most important species consumed and cultivated in Spain. Peppers
are a source of carotenoids and phenolic compounds widely associated with biological …

HER2 is overexpressed in about 20% of breast cancers and contributes to poor prognosis.
Unfortunately, a large fraction of patients have primary or acquired resistance to the HER2-…

The carcinogenic potential of dibenzo[a,l]pyrene (DBP) has been well characterized in
numerous animal models. We have previously documented that a single dose of 15 mg/Kg DBP …

Triple-negative breast cancer (TNBC) remains a disease with a paucity of targeted treatment
opportunities. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor …

The primary focus of chemoprevention research is the prevention of cancer using pharmacological,
biological, and nutritional interventions. Chemotherapeutic approaches that have …

This Review discusses the various types of non-coding oligonucleotides, which have garnered
extensive interest as new alternatives for targeted cancer therapies over small molecule …

Dibenzo(a,l)pyrene (DBP) is among the most potent carcinogenic polycyclic aromatic
hydrocarbons. Previously, we showed that DBP administration to pregnant mice resulted in high …