Present and future in vitro approaches for drug metabolism

S Ekins, BJ Ring, J Grace, DJ McRobie-Belle… - … of pharmacological and …, 2000 - Elsevier
The 1980s through 1990s witnessed the widespread incorporation of in vitro absorption,
distribution, metabolism, and excretion (ADME) approaches into drug development by drug …

Effects of gestational and overt diabetes on human placental cytochromes P450 and glutathione S-transferase

DJ McRobie, DD Glover, TS Tracy - Drug metabolism and disposition, 1998 - ASPET
The placenta possesses the ability to metabolize a number of xenobiotics and endogenous
compounds by processes similar to those seen in the liver. Animal and in vivo studies have …

Regiospecificity of placental metabolism by cytochromes P450 and glutathione S-transferase

DJ McRobie, DD Glover, TS Tracy - Gynecologic and obstetric …, 1996 - karger.com
The placenta possesses the ability to metabolize numerous xenobiotics and endogenous
steroids. However, it is unknown whether regional differences in these enzymatic reactions …

The effects of diabetes on placental aromatase activity

DJ McRobie, KR Korzekwa, DD Glover… - The Journal of steroid …, 1997 - Elsevier
Diabetes complicates 2–3% of all pregnancies and is associated with an increase in both
perinatal morbidity and mortality, though reasons for these adverse outcomes are unknown. …

Effects of gestational and overt diabetes on placental cytochromes P450 and glutathione S-transferase

DD Glover, DJ McRobie, TS Tracy - Primary Care Update for Ob/Gyns, 1998 - Elsevier
Objective: Animal and in vivo human studies have observed that diabetes alters the
expression of hepatic metabolizing cytochrome P450 (CYP) and glutathione S-transferase (GST) …

[BOOK][B] Placental xenobiotic and steroid metabolism in normal and diabetic patients

DJ McRobie-Belle - 1998 - search.proquest.com
The primary function of the human placenta is to ensure an optimal environment for fetal
growth and development. Nutrients, endogenous substances and xenobiotics enter the …

Grassroots innovation movements: challenges and contributions

A Smith, M Fressoli, H Thomas - Journal of Cleaner Production, 2014 - Elsevier
Technologies for social inclusion in Latin America are a recent manifestation of grassroots
innovation movements whose global activities go back to appropriate technology in the 1970s …

" Bringing me to where I am”: jazz autobiography in context

H Farrington - 2014 - repository.mdx.ac.uk
Jazz autobiography is an area largely unexplored in current academic discourse: a scattering
of articles and chapters in textbooks on jazz or African-American autobiography is all we …

[BOOK][B] Communicating gender

S Romaine - 1998 - taylorfrancis.com
Taking a cross-disciplinary approach, Suzanne Romaine's main concern is to show how
language and discourse play key roles in understanding and communicating gender and culture…

[BOOK][B] Pattern and Chaos in Art, Science and Everyday Life: Critical Intersections and Creative Practice

S Horton, V Mitchell - 2023 - books.google.com
This collection explores critical and visual practices through the lens of interactions and
intersections between pattern and chaos. The dynamic of the inter-relationship between pattern …