The Human Metabolome Database or HMDB ( https://hmdb.ca ) has been providing
comprehensive reference information about human metabolites and their associated biological, …

Metabonomics/metabolomics is an important science for the understanding of biological
systems and the prediction of their behaviour, through the profiling of metabolites. Two …

The Natural Products Magnetic Resonance Database (NP-MRD) is a comprehensive, freely
available electronic resource for the deposition, distribution, searching and retrieval of …

Taurine is one of the most abundant amino acids in mammalian tissues. It is obtained from
the diet and by de novo synthesis from cysteic acid or hypotaurine. Despite the discovery in …

We report the production and metabolic phenotype of a mouse line in which the Fmo5 gene
is disrupted. In comparison with wild-type (WT) mice, Fmo5 −/− mice exhibit a lean …

Introduction Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutations occur in
approximately one-third of colorectal (CRC) tumours and have been associated with poor …

It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase
5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-…

Coral reefs are suffering unprecedented declines in health state on a global scale. Some have
suggested that human assisted evolution or assisted gene flow may now be necessary to …

We previously showed that Fmo5 −/− mice exhibit a lean phenotype and slower metabolic
ageing. Their characteristics include lower plasma glucose and cholesterol, greater glucose …

Editorial Varshavi, Varshavi & Everett effects of the analgesic paracetamol. Subsequently,
this approach was demonstrated in humans in a study of the metabolism of the same drug …