Clinical disposition, metabolism and in vitro drug–drug interaction properties of omadacycline

J Flarakos, Y Du, H Gu, L Wang, HJ Einolf, DY Chun… - Xenobiotica, 2017 - Taylor & Francis
Absorption, distribution, metabolism, transport and elimination properties of omadacycline,
an aminomethylcycline antibiotic, were investigated in vitro and in a study in healthy male …

Physiologically based pharmacokinetic model predictions of panobinostat (LBH589) as a victim and perpetrator of drug-drug interactions

…, W Lin, CS Won, L Wang, H Gu, DY Chun… - Drug Metabolism and …, 2017 - ASPET
Panobinostat (Farydak) is an orally active hydroxamic acid–derived histone deacetylase
inhibitor used for the treatment of relapsed or refractory multiple myeloma. Based on …

Hydrogen production conditions from food waste by dark fermentation with Clostridium beijerinckii KCTC 1785

JK Kim, L Nhat, YN Chun, SW Kim - Biotechnology and Bioprocess …, 2008 - Springer
The optimum conditions for biological hydrogen production from food waste by Clostridium
beijerinckii KCTC 1875 were investigated. The optimum initial pH and fermentation …

Autoionizing Rydberg series of Ar investigated by stepwise excitations with lasers and synchrotron radiation

YY Lee, TY Dung, RM Hsieh, JY Yuh, YF Song, GH Ho… - Physical Review A, 2008 - APS
Synchrotron radiation is used to excite Ar to the intermediate states 3 p 1∕ 2 5 (3 d′[3∕ 2]
1, 5 d′[3∕ 2] 1, 5 s′[1∕ 2] 1, 7 s′[1∕ 2] 1) and 3 p 3∕ 2 5 (6 d [1∕ 2] 1, 6 d [3∕ 2] 1, 8 s …

[PDF][PDF] Recycling the past': Tzu-chi waste recycling and the cultural politics of nostalgia

YA Dung - Pan, 1982 - scholarlypublications …
In approximately the 1990s, recycling as we know it today swept into Taiwan as a social
movement, and successive endeavours have been implemented and contributed to the …

Direct fermentation of sweet potato to produce maximal hydrogen and ethanol

CY Chu, B Sen, CH Lay, YC Lin, CY Lin - Applied energy, 2012 - Elsevier
… g/L and an initial cultivation pH 8.5 with cow dung seed. The main soluble microbial products
(… concentration 200 g/L with cow dung seed. Cow dung was a good seed source for directly …

[HTML][HTML] Amikacin liposome inhalation suspension (ALIS) penetrates non-tuberculous mycobacterial biofilms and enhances amikacin uptake into macrophages

J Zhang, F Leifer, S Rose, DY Chun, J Thaisz… - Frontiers in …, 2018 - frontiersin.org
Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural
lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of …

Evaluation of clinical drug interaction potential of clofazimine using static and dynamic modeling approaches

R Sangana, H Gu, DY Chun, HJ Einolf - Drug metabolism and disposition, 2018 - ASPET
The 2016 World Health Organization treatment recommendations for drug-resistant
tuberculosis (DR-TB) positioned clofazimine as a core second-line drug. Being identified as a …

Simultaneous physiologically based pharmacokinetic (PBPK) modeling of parent and active metabolites to investigate complex CYP3A4 drug-drug interaction …

…, S Rebello, T Ouatas, L Wang, DY Chun… - Drug metabolism and …, 2018 - ASPET
Midostaurin (PKC412) is being investigated for the treatment of acute myeloid leukemia (AML)
and advanced systemic mastocytosis (advSM). It is extensively metabolized by CYP3A4 …

[CITATION][C] Supplemental Data to

HJ Einolf, W Lin, CS Won, L Wang, H Gu, DY Chun… - ASPET