Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration.

…, TB Vree, AM Baars, EF Termond… - European journal of …, 1989 - europepmc.org
Articaine is metabolized into articainic acid. The half-lives of articaine are 0.54+/-0.05 and
2.44+/-0.30 h and that of its metabolite, 2.44+/-0.30 h. Of the administered dose approximately …

Comparison of the pharmacokinetics of intravenously administered rac-baclofen and its (-)-(R)-and (+)-(S)-enantiomers in dogs.

EW Wuis, MJ Dirks, EF Termond, TB Vree… - … journal of clinical …, 1989 - europepmc.org
Comparison of the pharmacokinetics of intravenously administered rac-baclofen and its (-)-(R)-
and (+)-(S)-enantiomers in dogs. - Abstract - Europe PMC Sign in | Create an account https://orcid.org …

In vivo and in vitro pharmacokinetic differences between four structurally closely related anthracyclines in hematopoietic cell subtypes in humans.

PA Speth, PC Linssen, EF Termond… - Drug metabolism and …, 1989 - ASPET
Minor differences in chemical structure of adriamycin (ADM), 4'-epiadriamycin (E-ADM),
daunomycin (DNM), and 4-demethoxydaunomycin (D-DNM) lead to large differences between …

[CITATION][C] Pharmacokinetics of sulfonamide revisited.

TB Vree, YA Hekster, EF Termond… - Antibiotics and …, 1985 - europepmc.org
Pharmacokinetics of sulfonamide revisited. - Abstract - Europe PMC Sign in | Create an
account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us …

[CITATION][C] The pharmacokinetics of sulfapyridine and its N4-acetyl-, and hydroxy metabolites in man

…, MW Tijhuis, EF Termond - Journal of …, 1989 - pubmed.ncbi.nlm.nih.gov
… 1 , TB Vree, MW Tijhuis, EF Termond

Pharmacokinetics, metabolism and renal excretion of sulfatroxazole and its 5‐hydroxy‐ and N4‐acetylmetabolites in man

…, YA Hekster, MW Tijhuis, EFS Termond… - … & drug disposition, 1986 - Wiley Online Library
Hydroxylation is the predominant pathway of metabolism for sulfatroxazole in the body,
accounting for 70 per cent of the dose. Fifteen per cent of the dose is acetylated unimodally and …

Abstracts of papers

…, MW Tijhuis, JFM Nouws, E Termond… - Pharmaceutisch …, 1984 - Springer
… Our results indicate that the increase of free fraction of D due to heparin is only an in vitro ef
-medications and time between blood sampling and ingestion ef the last dose. We found an …

Clinical pharmacokinetics of carbamazepine and its epoxy and hydroxy metabolites in humans after an overdose

…, TJ Janssen, YA Hekster, EFS Termond… - Therapeutic drug …, 1986 - journals.lww.com
In five cases of carbamazepine (CBZ) intoxication, the time curves of the plasma concentration
and of the renal excretion rate of carbamazepine and its metabolites carbamazepine 10, …

Treatment of baclofen overdose by haemodialysis: a pharmacokinetic study

VC Wu, SL Lin, SM Lin, CC Fang - Nephrology Dialysis …, 2005 - academic.oup.com
Baclofen is currently used in the treatment of muscle spasticity, especially in patients with
multiple sclerosis or in patients with spinal or cerebral disorders. Baclofen is eliminated …

Baclofen unerotoxicity in a chronic haemodialysis patient

N Bassilios, V Launay‐Vacher… - Nephrology Dialysis …, 2000 - academic.oup.com
Four days after baclofen was initiated our patient treated with usual doses [2]. Therefore it has
been presented acute confusion and agitation. Neurological examination revealed muscle …