Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice

H Wei, L Tye, E Bresnick, DF Birt - Cancer research, 1990 - AACR
This investigation studied the effect of topical application of apigenin on skin tumorigenesis
initiated by 7,12-dimethylbenz(a)anthracene (DMBA) and promoted by 12-O-…

Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol

DF Birt, B Walker, MG Tibbels, E Bresnick - Carcinogenesis, 1986 - academic.oup.com
We assessed the anti-mutagenic and anti-promotion properties of two flavones, apigenin
and robinetin, and of indole-3-carbinol, because these compounds have been reported in …

Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes

DC Harmes, E Bresnick, EA Lubin, JK Watson… - Oncogene, 2003 - nature.com
Mammary epithelial regeneration implies the existence of cellular progenitors with retained
replicative capacity, prolonged lifespan and developmental potency. Evidence exists that ΔN-…

A system in mouse liver for the repair of O6-methylguanine lesions in methylated DNA

J M. Bogden, A Eastman, E Bresnick - Nucleic Acids Research, 1981 - academic.oup.com
An activity from mouse liver which catalyzes the disappearance of 0 6 - methylguanine from
DNA methylated with methylnitrosourea has been partially purified by ammonium sulfate …

Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue

E Bresnick, DF Birt, K Wolterman, M Wheeler… - …, 1990 - academic.oup.com
Mammary cancer was induced in female Sprague-Dawley rats by a single injection of N-methyl-N-nitrosourea
(MNU) and rats were randomized to control fat (5%) and high fat (24.6%) …

Irradiation-induced Expression of O6-Methylguanine-DNA Methyltransferase in Mammalian Cells

CL Chan, Z Wu, A Eastman, E Bresnick - Cancer research, 1992 - AACR
O 6 -Methylguanine-DNA methyltransferase (MGMT) is a DNA repair protein which plays an
important role in chemotherapy, mutagenesis, and carcinogenesis. The specific activity of …

Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints

AA Levesque, EA Kohn, E Bresnick, A Eastman - Oncogene, 2005 - nature.com
… This work is dedicated to the memory of our close friend and colleague Dr Edward Bresnick,
whose joy in his retirement was to return to the laboratory bench and participate in this …

End-product inhibition of thymidine kinase activity in normal and leukemic human leukocytes

E Bresnick, RJ Karjala - Cancer Research, 1964 - AACR
Thymidine kinase activity in sonicated soluble preparations obtained from normal and leukemic
human leukocytes (both chronic myelogenous and chronic lymphocytic leukemia) was …

Identification of positive and negative regulatory elements of the human cytochrome P4501A2 (CYP1A2) gene

I Chung, E Bresnick - Archives of biochemistry and biophysics, 1997 - Elsevier
We previously demonstrated an enhancer-like positive regulatory element within a 259-bp
sequence (−2352 to −2094 bp) of the humanCYP1A2gene in HepG2 cells. Three protein …

[HTML][HTML] Glycine N-methyltransferase is an example of functional diversity: role as a polycyclic aromatic hydrocarbon-binding receptor

R Bhat, E Bresnick - Journal of Biological Chemistry, 1997 - ASBMB
The cytochrome P-4501A1 (CYP1A1) gene is regulated by several trans-acting factors
including the 4 S polycyclic aromatic hydrocarbon (PAH)-binding protein, which has recently …