Poly (I: C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation

ER McColl, M Piquette‐Miller - American Journal of …, 2019 - Wiley Online Library
Problem Maternal immune activation (MIA) during pregnancy is associated with increased
chances of neurodevelopmental disorders including schizophrenia and autism spectrum …

COVID-19 vaccines and the virus: impact on drug metabolism and pharmacokinetics

ER McColl, MA Croyle, WC Zamboni, WG Honer… - Drug Metabolism and …, 2023 - ASPET
This article reports on an American Society of Pharmacology and Therapeutics, Division of
Drug Metabolism and Disposition symposium held at Experimental Biology on April 2, 2022, …

Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats

ER McColl, M Piquette-Miller - Placenta, 2021 - Elsevier
Introduction Maternal immune activation (MIA) is associated with neurodevelopmental
disorders in offspring. We previously demonstrated that poly(I:C)-mediated MIA alters placental …

[HTML][HTML] Impact of viral inflammation on the expression of renal drug transporters in pregnant rats

N Karimian Pour, ER McColl, M Piquette-Miller - Pharmaceutics, 2019 - mdpi.com
Inflammation impacts the expression and function of drug transporters at term-gestation;
however, the impact of inflammation on the expression of drug transporters at mid-gestation is …

Impact of inflammation and infection on the expression of amino acid transporters in the placenta: A minireview

ER McColl, M Hurtarte, M Piquette-Miller - Drug Metabolism and Disposition, 2022 - ASPET
Amino acid transporters expressed in the placenta help to regulate the transfer of amino acids
from maternal to fetal circulation. Nutritional or hormonal factors are known to potentially …

The effect of tobacco use on the expression of placental transporters in Alaska native women

ER McColl, J Kwok, NL Benowitz… - Clinical …, 2023 - Wiley Online Library
Prenatal tobacco use among Alaska Native (AN) women has decreased substantially over
the past two decades. Previous research suggests that providing AN women with feedback …

[HTML][HTML] Dysregulation of Amino Acid Transporters in a Rat Model of TLR7-Mediated Maternal Immune Activation

ER McColl, JT Henderson, M Piquette-Miller - Pharmaceutics, 2023 - mdpi.com
Maternal immune activation (MIA) during pregnancy is linked to neurodevelopmental disorders
in humans. Similarly, the TLR7 agonist imiquimod alters neurodevelopment in rodents. …

SLC neurotransmitter transporters as therapeutic targets for alcohol use disorder: a narrative review

ER McColl, M Piquette‐Miller - Alcoholism: Clinical and …, 2020 - Wiley Online Library
Alcohol use disorder (AUD) is 1 of the most prevalent of all substance use disorders and
contributes significantly to global disease burden. Despite its prevalence, <10% of individuals …

Dysregulation of solute carrier transporters in malaria‐infected pregnant mice

N Najjar, ER McColl, A Weckman, KC Kain… - Parasite …, 2019 - Wiley Online Library
Aims Malaria in pregnancy (MiP) alters the expression of ATP‐binding cassette efflux transporters
in maternal and foetal tissues, as well as the placenta. Malaria induces oxidative stress…

Battling the HIV/AIDS epidemic: triumphs and barriers

ER McColl, D Kojovic… - Clinical Pharmacology & …, 2018 - Wiley Online Library
Worldwide, over 77 million people have been infected by human immunodeficiency virus (
HIV ) but its cure remains elusive. Once considered a fatal disease, advances in antiretroviral …