Problem Maternal immune activation (MIA) during pregnancy is associated with increased
chances of neurodevelopmental disorders including schizophrenia and autism spectrum …

This article reports on an American Society of Pharmacology and Therapeutics, Division of
Drug Metabolism and Disposition symposium held at Experimental Biology on April 2, 2022, …

Introduction Maternal immune activation (MIA) is associated with neurodevelopmental
disorders in offspring. We previously demonstrated that poly(I:C)-mediated MIA alters placental …

Inflammation impacts the expression and function of drug transporters at term-gestation;
however, the impact of inflammation on the expression of drug transporters at mid-gestation is …

Amino acid transporters expressed in the placenta help to regulate the transfer of amino acids
from maternal to fetal circulation. Nutritional or hormonal factors are known to potentially …

Prenatal tobacco use among Alaska Native (AN) women has decreased substantially over
the past two decades. Previous research suggests that providing AN women with feedback …

Numerous SNPs have been linked to altered blood/tissue drug concentrations and increased
adverse drug effects.[4] Likewise, SNPs can alter either exposure or binding to drug …

Maternal immune activation (MIA) during pregnancy is linked to neurodevelopmental disorders
in humans. Similarly, the TLR7 agonist imiquimod alters neurodevelopment in rodents. …

Alcohol use disorder (AUD) is 1 of the most prevalent of all substance use disorders and
contributes significantly to global disease burden. Despite its prevalence, <10% of individuals …

Aims Malaria in pregnancy (MiP) alters the expression of ATP‐binding cassette efflux transporters
in maternal and foetal tissues, as well as the placenta. Malaria induces oxidative stress…