User profiles for Elizabeth Goodwin

Elizabeth Goodwin

Research Fellow, University of Exeter
Verified email at exeter.ac.uk
Cited by 299

The power of the 3′ UTR: translational control and development

S Kuersten, EB Goodwin - Nature Reviews Genetics, 2003 - nature.com
Many crucial decisions, such as the location and timing of cell division, cell-fate determination,
and embryonic axes establishment, are made in the early embryo, a time in development …

[HTML][HTML] The STAR protein, GLD‐1, is a translational regulator of sexual identity in Caenorhabditis elegans

E Jan, CK Motzny, LE Graves, EB Goodwin - The EMBO Journal, 1999 - embopress.org
The Caenorhabditis elegans sex determination gene, tra‐2, is translationally regulated by
elements in the 3′‐untranslated region called TGEs. TGEs govern the translation of mRNAs …

RNA target specificity of the STAR/GSG domain post-transcriptional regulatory protein GLD-1

…, LA Frater, DL Abramovitz, EB Goodwin… - Nature structural & …, 2004 - nature.com
The post-transcriptional regulation of gene expression underlies several critical developmental
phenomena. In metazoa, gene products that are expressed, silenced and packaged …

Health and well being of substance use disorder patients with and without posttraumatic stress disorder

P Ouimette, E Goodwin, PJ Brown - Addictive Behaviors, 2006 - Elsevier
While studies link posttraumatic stress disorder (PTSD) to substance use disorders (SUDs),
little is known about the health and functional status of patients with such comorbidity. This …

[HTML][HTML] Adverse event profile of pyrimethamine-based therapy in toxoplasmosis: a systematic review

RR Ben-Harari, E Goodwin, J Casoy - Drugs in R&D, 2017 - Springer
Introduction Approximately a third of the population worldwide is chronically infected with
Toxoplasma gondii. Pyrimethamine-based regimens are recommended for the treatment of …

The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines

…, M Pykett, EM Welch, K O'Keefe, R Kong, E Goodwin… - Virus research, 2021 - Elsevier
The coronavirus disease 2019 (COVID-19) pandemic has created an urgent need for
therapeutics that inhibit the SARS−COV-2 virus and suppress the fulminant inflammation …

College students' attitudes toward racial discrimination

F Biasco, EA Goodwin, KL Vitale - College Student Journal, 2001 - go.gale.com
The study of college students' attitudes toward racial discrimination was conducted among
students attending a northwest Florida university. The samples consisted of one-tenth of the …

Ataluren delays loss of ambulation and respiratory decline in nonsense mutation Duchenne muscular dystrophy patients

…, A Kristensen, F Bibbiani, E Goodwin… - Journal of …, 2021 - becarispublishing.com
Aim: We investigated the effect of ataluren plus standard of care (SoC) on age at loss of
ambulation (LoA) and respiratory decline in patients with nonsense mutation Duchenne …

The STAR protein QKI-6 is a translational repressor

…, E Punkay, K Artzt, EB Goodwin - Proceedings of the …, 1999 - National Acad Sciences
The signal transduction and activation of RNA (STAR) family of RNA-binding proteins, whose
members are evolutionarily conserved from yeast to humans, are important for a number of …

Nuclear translation: what is the evidence?

JE Dahlberg, E Lund, EB Goodwin - Rna, 2003 - rnajournal.cshlp.org
Recently, several reports have been published in support of the idea that protein synthesis
occurs in both the nucleus and the cytoplasm. This proposal has generated a great deal of …