Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial …
…, G Lindberg, C Einarsson, F Sjöqvist… - … of Pharmacology and …, 2001 - ASPET
This investigation describes the expression and interindividual variability in transcript levels
of multiple drug efflux systems in the human jejunum and compares the expression profiles …
of multiple drug efflux systems in the human jejunum and compares the expression profiles …
Use of doping agents, particularly anabolic steroids, in sports and society
F Sjöqvist, M Garle, A Rane - The Lancet, 2008 - thelancet.com
The use of doping agents, particularly anabolic androgenic steroids (AAS), has changed
from being a problem restricted to sports to one of public-health concern. We review the …
from being a problem restricted to sports to one of public-health concern. We review the …
The 'wise list'–a comprehensive concept to select, communicate and achieve adherence to recommendations of essential drugs in ambulatory care in Stockholm
…, D Schmidt, S Sjöberg, F Sjöqvist… - Basic & clinical …, 2011 - Wiley Online Library
The aim was to present and evaluate the impact of a comprehensive strategy over 10 years
to select, communicate and achieve adherence to essential drug recommendations (EDR) in …
to select, communicate and achieve adherence to essential drug recommendations (EDR) in …
Relationship between plasma level and therapeutic effect of nortriptyline
M Åsberg, B Crönholm, F Sjöqvist, D Tuck - Br Med J, 1971 - bmj.com
The relationship between plasma concentration of nortriptyline and therapeutic effect after
two weeks' treatment with the drug was investigated in 29 psychiatric inpatients. Endogenous …
two weeks' treatment with the drug was investigated in 29 psychiatric inpatients. Endogenous …
Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population
…, I Johansson, M Ingelman-Sundberg, F Sjöqvist - Biochemical and …, 1999 - Elsevier
Cytochrome P450 2C9 (CYP2C9) catalysis the metabolism of important drugs such as
phenytoin,S-warfarin, tolbutamide, losartan, torasemide, and nonsteroidal anti-inflammatory drugs…
phenytoin,S-warfarin, tolbutamide, losartan, torasemide, and nonsteroidal anti-inflammatory drugs…
Pharmacokinetics of losartan and its metabolite E‐3174 in relation to the CYP2C9 genotype
Background And Aim Losartan is metabolized by polymorphic CYP2C9 to E‐3174. Our aim
was to evaluate the pharmacokinetics of losartan and E‐3174 in relation to the CYP2C9 …
was to evaluate the pharmacokinetics of losartan and E‐3174 in relation to the CYP2C9 …
Increased Plasma Protein Binding of Propranolol and Chlorpromazine Mediated by Disease-Induced Elevations of Plasma α1 Acid Glycoprotein
…, I Odar-Cederlöf, C Johansson, F Sjöqvist - … England Journal of …, 1978 - Mass Medical Soc
To assess the importance of disease-induced increases in plasma concentrations of α 1
acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined …
acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined …
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds
W Hammer, F Sjöqvist - Life Sciences, 1967 - Elsevier
Imipramine counteracts the “depressive syndrome” evoked by reserpine in rats at a time
when the brain contains little imipramine (I) but high levels of the active metabolite …
when the brain contains little imipramine (I) but high levels of the active metabolite …
The anti-doping hot-line, a means to capture the abuse of doping agents in the Swedish society and a new service function in clinical pharmacology
…, AM Thurelius, M Garle, A Rane, F Sjöqvist - European journal of …, 2003 - Springer
With the support of the Swedish National Institute of Health a national information service was
started in 1993 aiming to capture the abuse of doping agents in the general public. It was …
started in 1993 aiming to capture the abuse of doping agents in the general public. It was …
Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population
…, M Ingelman‐Sundberg, F Sjöqvist - Clinical …, 1992 - Wiley Online Library
The molecular basis of polymorphic debrisoquin hydroxylation was studied in 223 Swedish
white subjects, 187 extensive metabolizers and 36 poor metabolizers phenotyped with …
white subjects, 187 extensive metabolizers and 36 poor metabolizers phenotyped with …