Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial …

…, G Lindberg, C Einarsson, F Sjöqvist… - … of Pharmacology and …, 2001 - ASPET
This investigation describes the expression and interindividual variability in transcript levels
of multiple drug efflux systems in the human jejunum and compares the expression profiles …

Use of doping agents, particularly anabolic steroids, in sports and society

F Sjöqvist, M Garle, A Rane - The Lancet, 2008 - thelancet.com
The use of doping agents, particularly anabolic androgenic steroids (AAS), has changed
from being a problem restricted to sports to one of public-health concern. We review the …

The 'wise list'–a comprehensive concept to select, communicate and achieve adherence to recommendations of essential drugs in ambulatory care in Stockholm

…, D Schmidt, S Sjöberg, F Sjöqvist… - Basic & clinical …, 2011 - Wiley Online Library
The aim was to present and evaluate the impact of a comprehensive strategy over 10 years
to select, communicate and achieve adherence to essential drug recommendations (EDR) in …

Relationship between plasma level and therapeutic effect of nortriptyline

M Åsberg, B Crönholm, F Sjöqvist, D Tuck - Br Med J, 1971 - bmj.com
The relationship between plasma concentration of nortriptyline and therapeutic effect after
two weeks' treatment with the drug was investigated in 29 psychiatric inpatients. Endogenous …

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population

…, I Johansson, M Ingelman-Sundberg, F Sjöqvist - Biochemical and …, 1999 - Elsevier
Cytochrome P450 2C9 (CYP2C9) catalysis the metabolism of important drugs such as
phenytoin,S-warfarin, tolbutamide, losartan, torasemide, and nonsteroidal anti-inflammatory drugs…

Pharmacokinetics of losartan and its metabolite E‐3174 in relation to the CYP2C9 genotype

…, P Dorado, A LLerena, F Sjöqvist… - Clinical …, 2002 - Wiley Online Library
Background And Aim Losartan is metabolized by polymorphic CYP2C9 to E‐3174. Our aim
was to evaluate the pharmacokinetics of losartan and E‐3174 in relation to the CYP2C9 …

Increased Plasma Protein Binding of Propranolol and Chlorpromazine Mediated by Disease-Induced Elevations of Plasma α1 Acid Glycoprotein

…, I Odar-Cederlöf, C Johansson, F Sjöqvist - … England Journal of …, 1978 - Mass Medical Soc
To assess the importance of disease-induced increases in plasma concentrations of α 1
acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined …

Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds

W Hammer, F Sjöqvist - Life Sciences, 1967 - Elsevier
Imipramine counteracts the “depressive syndrome” evoked by reserpine in rats at a time
when the brain contains little imipramine (I) but high levels of the active metabolite …

The anti-doping hot-line, a means to capture the abuse of doping agents in the Swedish society and a new service function in clinical pharmacology

…, AM Thurelius, M Garle, A Rane, F Sjöqvist - European journal of …, 2003 - Springer
With the support of the Swedish National Institute of Health a national information service was
started in 1993 aiming to capture the abuse of doping agents in the general public. It was …

Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

…, M Ingelman‐Sundberg, F Sjöqvist - Clinical …, 1992 - Wiley Online Library
The molecular basis of polymorphic debrisoquin hydroxylation was studied in 223 Swedish
white subjects, 187 extensive metabolizers and 36 poor metabolizers phenotyped with …