GSK977779 is a potent HM74a agonist evaluated for the treatment of dyslipidemia. The
disposition and metabolism of [ 14 C]GSK977779 (67.6 μmol/kg po) was studied in male and …

Propranolol (PL) bioavailability has been shown to increase substantially when it is administered
with a protein-rich meal. A change in metabolic capacity or tissue uptake, induced by …

A new method has been developed for the analysis of propranolol plus five major metabolites
in perfusate from isolated liver preparations, and also in rat serum and dog plasma. The …

The effects of the additionof surfactants to reagent solutions used for absorbance detection
after a postcolumn reaction, have been examined at concentrations above the critical micelle …

Daprodustat is an oral small molecule hypoxia‐inducible factor (HIF) prolyl hydroxylase
inhibitor (PHI) approved in Japan and the United States for the treatment of anemia associated …

The large increase in propranolol (PL) bioavailability when administered with food cannot
be entirely explained by a transient increase in hepatic blood flow. A change in metabolic …

Introduction Primary biliary cholangitis (PBC) is characterized by lymphocyte cell-induced
immune destruction of cholangiole. However, the immunological characteristics of peripheral …

Considering nonlinear aerodynamic forces and airfoil structure nonlinearity, aeroelasticity of
supersonic airfoil was researched. Using the bifurcation diagram, phase diagram and …

In this paper, the hypersonic aircraft model is divided into several substructures according to
its structure and shape characteristics. Furthermore, the hysteresis nonlinearity of wing-…

Through dynamics test and theoretical analysis about rubber bearings in Auto body’s sub-frame,
and the past research results of sinusoidal excitation, a hysteretic non-linear …