Estimating the unbound fraction of drugs in brain has become essential for the evaluation
and interpretation of the pharmacokinetics and pharmacodynamics of new central nervous …

Semi-automated high throughput screening for the inhibition of major human cytochrome
P450 enzymes (1A2, 2C9, 2C19, 2D6 and 3A4) expressed in Escherichia Coli (Cypex …

Multiple experimental neuroscience techniques rely on the use of general anaesthesia to
minimize the discomfort associated to animal restraint and to achieve a more effective control …

Microsampling, a reduced volume sampling method, has successfully gained attention at the
International Conference on Harmonization (ICH) level and established benefits support its …

The increasing integration and complexity of electronic system design requires a constant
evolution of the languages used and its associated design methods and tools. The Forum on …

… Data analysis was performed both by myself and Dr Giulia Vinco. Dr Giulia Vinco performed
… course; Dr Giovanni Cioffi and Dr Federica Ognibeni for performing the echocardiography of …

… La resistenza alla fatica torsionale è stata testata a temperatura ambiente (21±1 C), vincolando
gli strumenti a 3 mm di distanza dall’estremità e applicando loro una rotazione in senso …

The development of novel anticonvulsant drugs with improved efficacy for the treatment of
epilepsy is hindered by a lack of information regarding the quantitative relationship between …

α6* nicotinic acetylcholine receptors (nAChRs) are highly and selectively expressed by
mesostriatal dopamine (DA) neurons. These neurons are thought to mediate several behavioral …

The DATE conference will take place from 9 to 13 March 2020 at the AlpExpo congress
centre in Grenoble, France. Grenoble has a great number of assets such as its manufacturing …