The illudins are a family of fungal sesquiterpenes that have been studied as anti-tumor agents,
and they also have antibacterial activity. Over a four-year period, 25 304 fungal isolates (…

Extracts from 44 species of seaweed from Gran Canaria (Canary Islands, Spain) were
screened for the production of antibacterial and antifungal compounds against a panel of Gram-…

As a part of a screening programme developed to evaluate the antimicrobial activity of
basidiomycetes, 317 isolates representing 204 species collected in Spain were screened against …

Microbial natural products are the origin of most of the antibiotics on the market today.
However, research in antibiotics and natural products has declined significantly during the last …

The human multidrug resistance gene MDR3 encodes a P-glycoprotein that belongs to the
ATP-binding cassette transporter family (ABCB4). MDR3 is a critical trans-locator for …

Guggulipid is an extract of the guggul treeCommiphora mukul and has been widely used to
treat hyperlipidemia in humans. The plant sterol guggulsterone (GS) is the active agent in …

Farnesoid X receptor (FXR) is a nuclear receptor for bile acids. Ligand activated-FXR
regulates transcription of genes to allow feedback control of bile acid synthesis and secretion. …

In a screening of natural products with antifungal activity derived from endophytic fungi, we
detected a potent activity in a culture belonging to the form-genus Hormonema, isolated from …

HIV-1 integrase is a critical enzyme for replication of HIV, and its inhibition is one of the most
promising new drug strategies for anti-retroviral therapy, with potentially significant …

Infant‐carrying behavior among callitrichids seems to be a costly activity. Costs have been
related to the physical efforts of carrying the weight of very heavy infants and to the resulting …