User profiles for Francois A. Leblond
Francois LeblondGestionnaire et Chercheur senior, Liminal R&D Biosciences Verified email at liminalbiosciences.com Cited by 4359 |
Transplantation of mesenchymal stem cells promotes tissue regeneration in a glaucoma model through laser-induced paracrine factor secretion and progenitor cell …
…, PR Boulos, A Ammar, FA Leblond… - Stem …, 2013 - academic.oup.com
Among bone marrow cells, hematopoietic and mesenchymal components can contribute to
repair damaged organs. Such cells are usually used in acute diseases but few options are …
repair damaged organs. Such cells are usually used in acute diseases but few options are …
Drug metabolism in chronic renal failure
V Pichette, FA Leblond - Current drug metabolism, 2003 - ingentaconnect.com
Pharmacokinetic studies conducted in patients with CRF demonstrate that the nonrenal
clearance of multiple drugs is reduced. Although the mechanism by which this occurs is unclear, …
clearance of multiple drugs is reduced. Although the mechanism by which this occurs is unclear, …
Microencapsulation of living cells in semi-permeable membranes with covalently cross-linked layers
J Dusseault, FA Leblond, R Robitaille, G Jourdan… - Biomaterials, 2005 - Elsevier
Microencapsulation in semi-permeable membranes protects transplanted cells against immune
destruction. Microcapsule strength is critical. We describe a method to microencapsulate …
destruction. Microcapsule strength is critical. We describe a method to microencapsulate …
Studies on small (<350 μm) alginate‐poly‐L‐lysine microcapsules. III. Biocompatibility of smaller versus standard microcapsules
R Robitaille, JF Pariseau, FA Leblond… - … Research: An Official …, 1999 - Wiley Online Library
Microencapsulation of islets of Langerhans has been proposed as a means of preventing their
immune destruction following transplantation. Microcapsules of diameters <350 μm made …
immune destruction following transplantation. Microcapsules of diameters <350 μm made …
Studies on small (< 300 μm) microcapsules: II—Parameters governing the production of alginate beads by high voltage electrostatic pulses
JP Hallé, FA Leblond, JF Pariseau… - Cell …, 1994 - journals.sagepub.com
The size of microcapsules is a critical parameter in the immunoisolation of islets of Langerhans
by microencapsulation. The use of smaller capsules decreases the total implant volume …
by microencapsulation. The use of smaller capsules decreases the total implant volume …
Rationale for heating oxaliplatin for the intraperitoneal treatment of peritoneal carcinomatosis: a study of the effect of heat on intraperitoneal oxaliplatin using a murine …
N Piché, FA Leblond, L Sidéris, V Pichette… - Annals of …, 2011 - journals.lww.com
Objective: To study the effect of heat on the absorption of intraperitoneal (IP) oxaliplatin
using a murine model. Background: Because of its efficiency in the systemic treatment of …
using a murine model. Background: Because of its efficiency in the systemic treatment of …
Decreased in vivo metabolism of drugs in chronic renal failure
FA Leblond, L Giroux, JP Villeneuve… - Drug metabolism and …, 2000 - ASPET
Chronic renal failure (CRF) is associated with a decrease in renal excretion of drugs, but its
effects on the liver metabolism of xenobiotics are poorly defined. The objectives of this study …
effects on the liver metabolism of xenobiotics are poorly defined. The objectives of this study …
Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats
Chronic renal failure (CRF) leads to decreased drug renal clearance due to a reduction in
the glomerular filtration rate. However, little is known about how renal failure affects renal …
the glomerular filtration rate. However, little is known about how renal failure affects renal …
ESRD impairs nonrenal clearance of fexofenadine but not midazolam
…, P Le, H Sadr, J Naud, FA Leblond… - Journal of the …, 2009 - journals.lww.com
ESRD can affect the pharmacokinetic disposition of drugs subject to nonrenal clearance.
Cytochrome P450 (CYP) enzymes, including CYP3A, and multiple intestinal and hepatic drug …
Cytochrome P450 (CYP) enzymes, including CYP3A, and multiple intestinal and hepatic drug …
Reduced hepatic synthesis of calcidiol in uremia
…, C Demers, JL Petit, FA Leblond… - Journal of the …, 2010 - journals.lww.com
Calcidiol insufficiency is highly prevalent in chronic kidney disease (CKD), but the reasons
for this are incompletely understood. CKD associates with a decrease in liver cytochrome …
for this are incompletely understood. CKD associates with a decrease in liver cytochrome …