Enhanced solubility and stability of PEGylated liposomal paclitaxel: in vitro and in vivo evaluation

T Yang, FD Cui, MK Choi, JW Cho, SJ Chung… - International journal of …, 2007 - Elsevier
An improved PEGylated liposomal formulation of paclitaxel has been developed with the
purpose of improving the solubility of paclitaxel as well as the physicochemical stability of …

Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation

YM Yin, FD Cui, CF Mu, MK Choi, JS Kim… - Journal of Controlled …, 2009 - Elsevier
A microemulsion system of docetaxel was prepared and evaluated for its solubilization
capacity and oral bioavailability improvement. Based on a solubility study and pseudo ternary …

Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome

T Yang, MK Choi, FD Cui, JS Kim, SJ Chung… - Journal of Controlled …, 2007 - Elsevier
A sterically stabilized paclitaxel-loaded liposome tailored to target human breast cancer
cells was developed, thereby promoting the efficiency of intracellular delivery of paclitaxel …

The effects of mixed MPEG–PLA/Pluronic® copolymer micelles on the bioavailability and multidrug resistance of docetaxel

CF Mu, P Balakrishnan, FD Cui, YM Yin, YB Lee… - Biomaterials, 2010 - Elsevier
A mixed micelle that comprised of MPEG–PLA (MPP) and Pluronic ® copolymers was
developed for enhanced bioavailability and to overcome multidrug resistance of docetaxel in …

Liposome formulation of paclitaxel with enhanced solubility and stability

T Yang, FD Cui, MK Choi, H Lin, SJ Chung… - Drug …, 2007 - Taylor & Francis
Despite its strong antitumor activity, paclitaxel (Taxol®) has limited clinical applications due
to its low aqueous solubility and hypersensitivity caused by Cremophor® EL and ethanol …

Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor

R Yang, WS Shim, FD Cui, G Cheng, X Han… - International journal of …, 2009 - Elsevier
In our previous study, lung tumor-specific targeting of paclitaxel was achieved in mice by
intravenous administration of chitosan-modified paclitaxel-loaded PLGA nanoparticles (C-NPs-…

Antitumor effect of paclitaxel-loaded PEGylated immunoliposomes against human breast cancer cells

T Yang, MK Choi, FD Cui, SJ Lee, SJ Chung… - Pharmaceutical …, 2007 - Springer
Purpose The antitumor effect of paclitaxel-loaded PEGylated immunoliposome (PILs) was
investigated in breast cancer cell lines and the xenograft model. Methods Herceptin was …

Preparation and characteristic of vinorelbine bitartrate-loaded solid lipid nanoparticles

J You, F Wan, F de Cui, Y Sun, YZ Du… - International journal of …, 2007 - Elsevier
A hydrophilic and temperature-induced degradation drug, vinorelbine bitartrate (VB)-loaded
solid lipid nanoparticles (SLNs) were prepared by a cold homogenization technique. The …

Folate-conjugated polymer micelles for active targeting to cancer cells: preparation, in vitro evaluation of targeting ability and cytotoxicity

J You, X Li, F de Cui, YZ Du, H Yuan… - Nanotechnology, 2008 - iopscience.iop.org
To obtain an active-targeting carrier to cancer cells, folate-conjugated stearic acid grafted
chitosan oligosaccharide (Fa-CSOSA) was synthesized by 1-ethyl-3-(3-dimethylaminopropyl) …

Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro

F Wan, J You, Y Sun, XG Zhang, FD Cui, YZ Du… - International journal of …, 2008 - Elsevier
In this study, the conjugate of PEG 2000 –stearic acid (PEG 2000 –SA) was used to prepare
PEGylated solid lipid nanoparticles loading vinorelbine bitartrate (VB-pSLNs) by cold …