User profiles for Günther Hochhaus
Gunther HochhausProfessor, University of Florida Verified email at cop.ufl.edu Cited by 7673 |
How the lung handles drugs: pharmacokinetics and pharmacodynamics of inhaled corticosteroids
J Winkler, G Hochhaus, H Derendorf - Proceedings of the American …, 2004 - atsjournals.org
Bronchial asthma and allergic rhinitis are among the most common diseases of modern society
and to an increasing degree a major cause of illness, hospitalization, loss of productivity, …
and to an increasing degree a major cause of illness, hospitalization, loss of productivity, …
A pharmacokinetic simulation tool for inhaled corticosteroids
B Weber, G Hochhaus - The AAPS journal, 2013 - Springer
The pharmacokinetic (PK) behavior of inhaled drugs is more complicated than that of other
forms of administration. In particular, the effects of certain physiological (mucociliary …
forms of administration. In particular, the effects of certain physiological (mucociliary …
Pharmacodynamics of omalizumab: implications for optimised dosing strategies and clinical efficacy in the treatment of allergic asthma
G Hochhaus, L Brookman, H Fox… - … medical research and …, 2003 - Taylor & Francis
Objective: Omalizumab (Xolair ), is a recombinant humanised monoclonal anti-immunoglobulin
E (IgE) antibody, for the treatment of allergic asthma. This review describes how the …
E (IgE) antibody, for the treatment of allergic asthma. This review describes how the …
Urgent appeal from international society for aerosols in medicine (ISAM) during COVID-19: clinical decision makers and governmental agencies should consider the …
…, MB Dolovich, I Gonda, G Hochhaus… - Journal of aerosol …, 2020 - liebertpub.com
The present COVID-19 pandemic caused by the SARS-CoV-2 has resulted in massive
disruption to the normal operation of societies worldwide. There is currently the prospect of a …
disruption to the normal operation of societies worldwide. There is currently the prospect of a …
Pharmacokinetic aspects of biotechnology products
In recent years, biotechnologically derived peptide and protein-based drugs have developed
into mainstream therapeutic agents. Peptide and protein drugs now constitute a substantial …
into mainstream therapeutic agents. Peptide and protein drugs now constitute a substantial …
Pharmacokinetics of the dietary supplement creatine
AM Persky, GA Brazeau, G Hochhaus - Clinical pharmacokinetics, 2003 - Springer
Creatine is a nonessential dietary component that, when supplemented in the diet, has shown
physiological benefits in athletes, in animal-based models of disease and in patients with …
physiological benefits in athletes, in animal-based models of disease and in patients with …
Receptor‐based pharmacokinetic‐pharmacodynamic analysis of corticosteroids
H Derendorf, G Hochhaus, H Mölimann… - The Journal of …, 1993 - Wiley Online Library
The pharmacodynamics of three corticosteroids were investigated after intravenous
administration of the phosphate esters of methylprednisolone, dexamethasone, and triamcinolone …
administration of the phosphate esters of methylprednisolone, dexamethasone, and triamcinolone …
Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticosteroids
M Hübner, G Hochhaus… - … and Allergy Clinics, 2005 - immunology.theclinics.com
Glucocorticoids are important anti-inflammatory substances that play a major role in the
treatment of local and systemic inflammations. Knowledge about the pharmacokinetics and …
treatment of local and systemic inflammations. Knowledge about the pharmacokinetics and …
Pharmacokinetic/pharmacodynamic aspects of aerosol therapy using glucocorticoids as a model
G Hochhaus, H Möllmann, H Derendorf… - The Journal of …, 1997 - Wiley Online Library
Glucocorticoids are predominantly prescribed in asthma therapy as aerosols to achieve high
pulmonary effects with reduced systemic spill‐over and pronounced pulmonary selectivity. …
pulmonary effects with reduced systemic spill‐over and pronounced pulmonary selectivity. …
Pharmacokinetics of triamcinolone acetonide after intravenous, oral, and inhaled administration
H Derendorf, G Hochhaus, S Rohatagi… - The Journal of …, 1995 - Wiley Online Library
The pharmacokinetics of triamcinolone acetonide were studied after intravenous (2 mg), oral
(5 mg), and inhaled (2 mg) administration. Triamcinolone acetonide concentrations were …
(5 mg), and inhaled (2 mg) administration. Triamcinolone acetonide concentrations were …