Incorporation of 6-thioguanine into nucleic acids
GA LePage - Cancer Research, 1960 - AACR
A method was devised by which 6-thioguanine-8-C 14 can be synthesized on a small scale
in a 63 per cent yield. The product was used to establish that Ehrlich ascites cells …
in a 63 per cent yield. The product was used to establish that Ehrlich ascites cells …
Biological energy transformations during shock as shown by tissue analyses
GA LePage - American Journal of Physiology-Legacy …, 1946 - journals.physiology.org
NOBLE-COLLIP SHOCK. The theoretical aspects of the metabolic events associated with
the shock syndrome have been discussed in the preceding paper (1). Students of cellular …
the shock syndrome have been discussed in the preceding paper (1). Students of cellular …
Basic biochemical effects and mechanism of action of 6-thioguanine
GA LePage - Cancer research, 1963 - AACR
… has been reported by LePage and Jones (7). It was established … LEPAGE,GA, and JONES,M.
Purinethiols as Feedback Inhibitors of Purine Synthesis in Ascites Tumor Cells. Cancer Res.…
Purinethiols as Feedback Inhibitors of Purine Synthesis in Ascites Tumor Cells. Cancer Res.…
The nutrition of tumors; a review.
JF Henderson, GA LePage - Cancer Research, 1959 - cabdirect.org
The nutrition of tumors ; a review. Cookies on CAB Direct Like most websites we use cookies.
This is to ensure that we give you the best experience possible. Continuing to use www.cabdirect.org …
This is to ensure that we give you the best experience possible. Continuing to use www.cabdirect.org …
In Vitro Incorporation of Glycine-2-C14 into Purines and Proteins
GA LePage - Cancer Research, 1953 - AACR
In vitro experiments with whole-cell preparations of Ehrlich carcinoma, Gardner lymphosarcoma,
and mouse liver led to extensive incorporation of glycine-2-C 14 into the cell proteins …
and mouse liver led to extensive incorporation of glycine-2-C 14 into the cell proteins …
Improved antitumor effects in 3'-branched homologs of 2'-deoxythioguanine. Synthesis and evaluation of thioguanine nucleosides of 2, 3-dideoxy-3-(hydroxymethyl)-D …
…, DW Henry, CE Cass, GA LePage - Journal of Medicinal …, 1979 - ACS Publications
The 3-(hydroxymethyl) branched homologue of 2-deoxyribofuranose was synthesized from
the corresponding branched ribofuranose 2-Q-(S-methyl dithiocarbonate) with tributyltin …
the corresponding branched ribofuranose 2-Q-(S-methyl dithiocarbonate) with tributyltin …
Intracellular Distribution of Radioactivity in Nucleic Acid Nucleotides and Proteins Following Simultaneous Administration of P32 and Glycine-2-C14
EP Tyner, C Heidelberger, GA LePage - Cancer Research, 1953 - AACR
… with the in vitro work of LePage (3@),who has studied nucleic acid purine synthesis in
Ehnlich … LEPAGE,GA In Vitro Incorporation of Glycine-2-C'4 into Purines and Proteins. Cancer …
Ehnlich … LEPAGE,GA In Vitro Incorporation of Glycine-2-C'4 into Purines and Proteins. Cancer …
Enhancement of the antitumor activity of arabinofuranosyladenine by 2′-deoxycoformycin
GA LePage, LS Worth, AP Kimball - Cancer Research, 1976 - AACR
The 6C3HED lymphosarcoma, a tumor cell line very sensitive to 9-β-d-arabinofuranosyladenine
(ara-A), and 6C3HED/ara-A, a line resistant to ara-A, were studied. Both were …
(ara-A), and 6C3HED/ara-A, a line resistant to ara-A, were studied. Both were …
Metabolic Effects of 9-d-Arabinosylpurines in Ascites Tumor Cells
JJ Brink, GA LePage - Cancer Research, 1964 - AACR
Spongoadenosine (9-β-d-arabinofuranosyladenine) was found to inhibit the growth of TA3
and 6C3HED ascites tumors. The growth of L1210 tumors was only slightly affected. Mice …
and 6C3HED ascites tumors. The growth of L1210 tumors was only slightly affected. Mice …
[PDF][PDF] Studies of 9-β-D-arabinofuranosyladenine in man
GA LePage, A KHALIQ, JA Gottlieb - Drug Metabolism and Disposition, 1973 - Citeseer
Materials and Methods Informed consent was obtained from all patients involved in the study.
Ara-A was supplied by Parke, Davis and Co., through Drug Research and Development, …
Ara-A was supplied by Parke, Davis and Co., through Drug Research and Development, …