User profiles for Ganesh Cherala

Ganesh Cherala

BioMarin Pharmaceutical Inc.
Verified email at bmrn.com
Cited by 1438

A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer

JJ Alumkal, R Slottke, J Schwartzman, G Cherala… - Investigational new …, 2015 - Springer
Introduction Diets high in cruciferous vegetables are associated with lower risk of incidence
of prostate cancer, including aggressive forms of this disease. Human intervention studies …

Impact of obesity on oral contraceptive pharmacokinetics and hypothalamic–pituitary–ovarian activity

AB Edelman, NE Carlson, G Cherala, MY Munar… - Contraception, 2009 - Elsevier
BACKGROUND: This study was conducted to determine whether increased body mass index
(BMI) affects oral contraceptive (OC) pharmacokinetics and suppression of hypothalamic–…

Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review

AB Edelman, G Cherala, FZ Stanczyk - Contraception, 2010 - Elsevier
The effect of obesity on drug metabolism and pharmacokinetics is poorly understood, and
this is particularly true in regard to contraceptive steroids. This article will review the known …

Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry

DR Koop, LA Bleyle, M Munar, G Cherala… - … of Chromatography B, 2013 - Elsevier
Long term therapeutic drug monitoring and assessment of renal function are required in renal
transplant recipients on immunosuppressant therapy such as tacrolimus. Dry blood spots (…

Impact of obesity on the pharmacokinetics of levonorgestrel-based emergency contraception: single and double dosing

AB Edelman, G Cherala, SW Blue, DW Erikson… - Contraception, 2016 - Elsevier
Objective To determine if differences exist in the pharmacokinetics (PK) of levonorgestrel-based
emergency contraception (LNG-EC) in obese and normal body mass index (BMI) users …

Association of platelet responsiveness with clopidogrel metabolism: role of compliance in the assessment of “resistance”

V Serebruany, G Cherala, C Williams, S Surigin… - American heart …, 2009 - Elsevier
BACKGROUND: Noncompliance is probably the major cause of clopidogrel “resistance.”
However, noncompliance is difficult to prove without confirming that the drug has been …

[HTML][HTML] Double dosing levonorgestrel-based emergency contraception for individuals with obesity: a randomized controlled trial

…, JD Hennebold, K Bond, JY Lim, G Cherala… - Obstetrics & …, 2022 - journals.lww.com
Ganesh Cherala was involved in this study as a private consultant. He is employed by
Gilead Sciences, which was not involved in this research. The other authors did not report any …

Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters

…, GH Marracci, MY Munar, G Cherala… - Multiple Sclerosis …, 2010 - journals.sagepub.com
Lipoic acid is a natural anti-oxidant available as an oral supplement from a number of different
manufacturers. Lipoic acid administered subcutaneously is an effective therapy for murine …

Prolonged monitoring of ethinyl estradiol and levonorgestrel levels confirms an altered pharmacokinetic profile in obese oral contraceptives users

AB Edelman, G Cherala, MY Munar, B DuBois… - Contraception, 2013 - Elsevier
BACKGROUND: Pharmacokinetic (PK) parameters based on short sampling times (48 h or
less) may contain inaccuracies due to their dependency on extrapolated values. This study …

Daptomycin pharmacokinetics in adult oncology patients with neutropenic fever

JS Bubalo, MY Munar, G Cherala… - Antimicrobial agents …, 2009 - Am Soc Microbiol
Daptomycin is the first antibacterial agent of the cyclic lipopeptides with in vitro bactericidal
activity against gram-positive organisms, including vancomycin-resistant enterococci, …