The resin of Pinus massoniana Lamb. contains, in addition to those isolated in an earlier
study, two new diterpene acids, viz. 15-hydroxy-7,13-abietadien-12-on-18-oic acid and 8(14)-…

Eight new cardenolide glycosides, 19-deoxyuscharin (1b), 4′β-hydroxygomphoside (1k), 3′-didehydrogomphoside
(1d), 3′-epigomphoside (1e), 3′-epiafroside (2e), 3′-…

Purpose PC SPES is an eight-component herbal product marketed for the treatment of prostate
cancer. The manufacturer of PC SPES claims that the herbal combination is a synergistic …

Asclepias vestita from Commatti Canyon in California has yielded nine new 19-oxo cardenolide
glycosides and one genin, all with the 5(6) double-bond, viz 5,6-dehydrocalactin, 5,6-…

The 4,6-dideoxyhexosulose moiety of gomphoside (1) and afroside (2) has been shown to
have the 1′S,2′S,3′R,5′R configuration, Formation of 2′,3′-OO-isopropylidene …

Purpose Cyathocline purpurea has been traditionally used to treat various diseases
including cancers for many years. However, these applications of C. purpurea have not been …

In an effort to improve the selectivity of the anticancer drug methotrexate (MTX), a series of
potential prodrugs in which the 2-amino group was acylated with various α-amino acids (as …

Eight cardenolide glycosides and one genin, including two new glucoside conjugates, have
been isolated from adult monarch butterflies (Danaus plexippus L.) the larvae of which were …

The anti-inflammatory glucocorticosteroid beclomethasone dipropionate was found
previously to degrade in human plasma at 37C to yield beclomethasone 17-monopropionate, …

The identity of eriocarpin with desglucosyrioside (1) has been established by comparison of
their triacetates. 13C and 1H Nmr spectra show that the conversion of labriformidin into …