Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples

W Brand, MG Boersma, H Bik… - Drug metabolism and …, 2010 - ASPET
Phase II metabolism by UDP-glucuronosyltransferases (UGTs) and sulfotransferases (SULTs)
is the predominant metabolic pathway during the first-pass metabolism of hesperetin (4′-…

Conjugation of Hesperetin by Individual UDP-Glucuronosyl Transferase (UGT) and Sulfotransferase (SULT) Isoforms

W Brand, H Bik, EF van den Hil, MG Boersma, W Meinl… - researchgate.net
Figure 3. Regioselective catalytic efficiencies (Vmax/Km) of the formation of hesperetin 7-O-sulfate
(A) and 3’-O-sulfate (B) by individual SULT isoforms. SULT1A2,-1C2 and-1E1 …

Functional disparity among BCL-2 members in tonsillar and leukemic B cell subsets probed by next generation BH3 mimetic profiling

V Peperzak, R Thijssen, H ter Burg, E Slinger, AP Kater… - Cancer Research, 2016 - AACR
… -only sensitizer BIK, which may explain why BCL-XL is not required for GC B cell survival. …
In contrast to GC B cells, BIK is absent in CLL cells while NOXA is highly expressed and, like …

A conversation with the artists Ronald Glasbergen

L Bik, J Lieshout - The Value of Culture: On the Relationship …, 1996 - books.google.com
Bik: I think it is allright that the government provides a little less money. This whole subsidy
system is a state business; everyone here considers it as such. As a consequence, many …

Climate impact on ecosystem changes and human responses during the Last Glacial and Early Holocene: A contribution to the INTIMATE (INTegration of Ice-core …

WZ Hoek, E Robinson, V Gelorini - Quaternary International, 2015 - Elsevier
The objective of INTIMATE [http://intimate. nbi. ku. dk/] is to reconstruct past abrupt and
extreme climate changes over the period 60,000–8000 years ago, by facilitating INTegration of …

[BOOK][B] Architecture and elite culture in the united Provinces, England and Ireland, 1500-1700

H Ronnes - 2006 - books.google.com
This study aims to elucidate concepts of castle in the Netherlands, England and Ireland in both
past and present times. The first part of the book examines current, respectively, academic…

Environmental (in) equity in the Netherlands-A case study on the distribution of environmental quality in the Rijnmond region

H Kruize, AA Bouwman - RIVM Rapport 550012003, 2004 - rivm.openrepository.com
… In this project, performed by Hanneke Kruize (RIVM), the socioeconomic differences in
local (perceived) environmental quality and causes of these differences are analysed, with an …

Artist teachers and democratic pedagogy

M Hoekstra - 2018 - chesterrep.openrepository.com
… The program does not qualify for a teaching position and a successful BIK artist is in fact
advised to maintain his or her outsider position as a visiting artist and not work too many hours …

[HTML][HTML] Metabolic syndrome parameters, determinants, and biomarkers in adult survivors of childhood cancer: protocol for the Dutch childhood cancer survivor study …

V Pluimakers, M Fiocco, J van Atteveld… - JMIR research …, 2021 - researchprotocols.org
Background: Potential late effects of treatment for childhood cancer include adiposity, insulin
resistance, dyslipidemia, and hypertension. These risk factors cluster together as metabolic …

[HTML][HTML] Induction of monocyte proliferation and HIV expression by IL-3 does not interfere with anti-viral activity of zidovudine

H Schuitemaker, NA Kootstra, MHJ van Oers… - Blood, 1990 - Elsevier
Myelosuppression is a major symptom in the acquired immunodeficiency syndrome (AIDS).
Moreover zidovudine, an anti-retroviral drug used to treat AIDS patients has …